Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
| ▸ | STAT5B | P51692 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4563268 | 0.90 | P2RX7 (0.32) | P2RX7PTGESPOLB | |
| SCHEMBL7579993 | 0.89 | P2RX7 (0.32) | P2RX7PTGES | |
| SCHEMBL3850724 | 0.88 | P2RX7 (0.33) | P2RX7PTGESSTAT3STAT5B | |
| SCHEMBL6038413 | 0.87 | P2RX7 (0.32) | P2RX7PTGESSTAT3STAT5B | |
| SCHEMBL4446033 | 0.86 | BRAF (0.31) | — | |
| SCHEMBL3850821 | 0.84 | P2RX7 (0.34) | P2RX7PTGESSTAT3STAT5B | |
| SCHEMBL3851267 | 0.83 | P2RX7 (0.33) | P2RX7PTGESSTAT3STAT5B | |
| SCHEMBL3852344 | 0.82 | P2RX7 (0.32) | P2RX7PTGESSTAT3STAT5B | |
| SCHEMBL3870071 | 0.81 | P2RX7 (0.32) | P2RX7PTGES | |
| SCHEMBL3850404 | 0.81 | P2RX7 (0.32) | P2RX7PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592386-A4 | COMPOSITION FOR AND TREATMENT OF DEMYELINATING DISEASES AND PARALYSIS BY ADMINISTRATION OF REMYELINATING AGENTS | ELAN PHARM INC (US) | 2007-06-13 | — | — | EP | disclosed |
| EP-1592386-A2 | COMPOSITION FOR AND TREATMENT OF DEMYELINATING DISEASES AND PARALYSIS BY ADMINISTRATION OF REMYELINATING AGENTS | Elan Pharmaceuticals, Inc. (US) | 2005-11-09 | — | — | EP | disclosed |
| WO-2004066931-A2 | COMPOSITION FOR AND TREATMENT OF DEMYELINATING DISEASES AND PARALYSIS BY ADMINISTRATION OF REMYELINATING AGENTS | ELAN PHARMACEUTICALS INC. (US) | 2004-08-12 | — | — | WO | disclosed |