Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
| ▸ | STAT5B | P51692 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6679476 | 0.90 | BMP1 (0.31) | — | |
| SCHEMBL3850724 | 0.88 | P2RX7 (0.33) | P2RX7PTGESSTAT3STAT5BF2 | |
| SCHEMBL3851267 | 0.88 | P2RX7 (0.33) | P2RX7PTGESSTAT3STAT5BF2 | |
| SCHEMBL5609005 | 0.87 | P2RX7 (0.32) | P2RX7PTGESSTAT3STAT5B | |
| SCHEMBL3850404 | 0.86 | P2RX7 (0.32) | P2RX7PTGESF2 | |
| SCHEMBL3870071 | 0.86 | P2RX7 (0.32) | P2RX7PTGES | |
| SCHEMBL3850821 | 0.86 | P2RX7 (0.34) | P2RX7PTGESSTAT3STAT5BF2 | |
| SCHEMBL3852344 | 0.83 | P2RX7 (0.32) | P2RX7PTGESSTAT3STAT5BF2 | |
| SCHEMBL3855382 | 0.83 | MCL1 (0.32) | P2RX7PTGES | |
| SCHEMBL7579993 | 0.82 | P2RX7 (0.32) | P2RX7PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060004019-A1 | Steroid sparing agents and methods of using same | BIOGEN IDEC INTERNATIONAL HOLDING LTD. (BM) | 2006-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004019-A1 | Steroid sparing agents and methods of using same | IL5, FCER2, CD40 | P2RX7 2510/4885PTGES 581/4885STAT3 1618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.