SCHEMBL5609264

SCHEMBL5609264

CCP(c1ccccc1)c1ccccc1F

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.33
KDM4E B2RXH2 2/20 0.33
CYP3A4 P08684 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
PSIP1 O75475 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.31
LMNA P02545 1/20 0.31
HPGD P15428 1/20 0.31
HTT P42858 1/20 0.31
ALDH1A1 P00352 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3386599 0.85 CYP3A4 (0.39) CYP3A4TDP1PSIP1SMN1; SMN2LMNA
SCHEMBL3679156 0.82 CYP3A4 (0.33) ACHECYP3A4TDP1
SCHEMBL34614 0.78 CYP3A4 (0.45) ACHEKDM4ECYP3A4TDP1PSIP1
SCHEMBL7191467 0.78 ACHE (0.36) ACHECYP3A4TDP1HTTALDH1A1
SCHEMBL18632029 0.77 CYP3A4 (0.30) CYP3A4TDP1
SCHEMBL28335448 0.76 ALDH1A1 (0.38) CYP3A4TDP1HPGDALDH1A1TP53
Hydrochloric Acid SCHEMBL11570690 0.75 CYP3A4 (0.43) ACHEKDM4ECYP3A4TDP1PSIP1
SCHEMBL3749691 0.75 CYP3A4 (0.43) ACHEKDM4ECYP3A4TDP1PSIP1
SCHEMBL8384147 0.75 CYP3A4 (0.43) ACHEKDM4ECYP3A4TDP1PSIP1
Ammonia Solution, Strong SCHEMBL15124087 0.75 CYP3A4 (0.43) ACHEKDM4ECYP3A4TDP1PSIP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007102955-A2 IN-LINE PROCESS FOR GENERATING COMONOMER EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2007-09-13 WO disclosed