SCHEMBL5609303

SCHEMBL5609303

C=CC=CC=C(CCCC)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 3/20 0.38
CES1 P23141 2/20 0.37
CES2 O00748 1/20 0.37
ALDH1A1 P00352 3/20 0.34
AKR1B1 P15121 1/20 0.34
TP53 P04637 1/20 0.34
PPARG P37231 6/20 0.33
PPARD Q03181 6/20 0.33
PPARA Q07869 6/20 0.33
GPR84 Q9NQS5 5/20 0.33
HDAC11 Q96DB2 5/20 0.33
TSHR P16473 4/20 0.33
TLR2 O60603 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
FABP4 P15090 2/20 0.33
PTPN1 P18031 2/20 0.33
SLC22A6 Q4U2R8 1/20 0.33
SLC22A8 Q8TCC7 1/20 0.33
GRIK1 P39086 1/20 0.33
MEN1 O00255 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8586760 0.86 CES1 (0.41) APEX1CES1CES2ALDH1A1AKR1B1
SCHEMBL8586757 0.86 CES1 (0.41) APEX1CES1CES2ALDH1A1AKR1B1
Monomethyl Fumarate SCHEMBL11325267 0.84 HCAR2 (0.45) APEX1ALDH1A1TSHRTDP1PTPN1
SCHEMBL1160283 0.83 CAMK2A (0.38) GPR84FFAR1FFAR4
SCHEMBL88045 0.82 CES1 (0.48) APEX1CES1CES2ALDH1A1AKR1B1
SCHEMBL8089512 0.82 CES1 (0.48) APEX1CES1CES2ALDH1A1AKR1B1
SCHEMBL28694016 0.81 AKR1B1 (0.46) CES1CES2ALDH1A1AKR1B1PPARG
SCHEMBL464973 0.80 ALDH1A1 (0.36) ALDH1A1TSHRGRIK1
SCHEMBL31622773 0.79 GPR84 (0.48) APEX1CES1CES2ALDH1A1AKR1B1
SCHEMBL1031366 0.79 PTPN1 (0.47) APEX1CES1CES2ALDH1A1AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3430080-A1 THERMOPLASTIC MOULDING COMPOUND BASED ON VINYLAROMATIC COPOLYMERS FOR 3D PRINTING INEOS Styrolution Group GmbH (DE) 2019-01-23 EP disclosed
EP-3274385-A1 PROCESS FOR PRODUCING THERMOPLASTIC POLYMER COMPOSITIONS WITH OPTIMIZED DEGREE OF CROSSLINKING INEOS Styrolution Group GmbH (DE) 2018-01-31 EP disclosed
EP-3083824-B1 MOULDING COMPOSITIONS BASED ON VINYLAROMATIC COPOLYMERS FOR 3D PRINTING INEOS STYROLUTION GROUP GMBH (DE) 2017-09-27 EP disclosed
WO-2017158075-A1 THERMOPLASTIC MOULDING COMPOUND BASED ON VINYLAROMATIC COPOLYMERS FOR 3D PRINTING INEOS STYROLUTION GROUP GMBH (DE) 2017-09-21 WO disclosed
EP-2035472-B1 ACRYLATE-VINYL AROMATIC-UNSATURATED NITRILE GRAFT COPOLYMER WITH EXCELLENT IMPACT STRENGTH, COLORABILITY, AND WEATHERABILITY, AND THERMOPLASTIC RESIN COMPOSITION CONTAINING THE SAME SAMSUNG SDI CO LTD (KR) 2017-04-19 EP disclosed
EP-3083824-A1 MOULDING COMPOSITIONS BASED ON VINYLAROMATIC COPOLYMERS FOR 3D PRINTING INEOS Styrolution Europe GmbH (DE) 2016-10-26 EP disclosed
WO-2016150999-A1 PROCESS FOR PRODUCING THERMOPLASTIC POLYMER COMPOSITIONS WITH OPTIMIZED DEGREE OF CROSSLINKING INEOS STYROLUTION GROUP GMBH (DE) 2016-09-29 WO disclosed
WO-2015091817-A1 MOULDING COMPOSITIONS BASED ON VINYLAROMATIC COPOLYMERS FOR 3D PRINTING STYROLUTION GROUP GMBH (DE) 2015-06-25 WO disclosed
US-8367770-B2 Acrylate-vinyl aromatic-unsaturated nitrile graft copolymer with excellent impact strength, colorability, and weatherability, and thermoplastic resin composition containing the same CHEIL INDUSTRIES INC. (KR) 2013-02-05 US disclosed
US-20070287799-A1 Acrylate-Vinyl Aromatic-Unsaturated Nitrile Graft Copolymer with Excellent Impact Strength, Colorability, and Weatherability, and Thermoplastic Resin Composition Containing the Same CHEIL INDUSTRIES INC. (KR) 2007-12-13 US disclosed
US-4957649-A POLYALKENESUCCINAMIDE, MONO-OR DIGLYCERIDE, METAL SALT OF A DIHYDROCARBYL DITHIOPHOSPHORIC ACID THE LUBRIZOL CORPORATION (US) 1990-09-18 US disclosed
US-4952328-A FOR INTERNAL COMBUSTION ENGINES THE LUBRIZOL CORPORATION (US) 1990-08-28 US disclosed
US-4941984-A LUBRICATING OIL, DETERGENTS OF MAGNESIUM SALTS, A SUCCINIC ACID ACYLATED POLYAMINE THE LUBRIZOL CORPORATION (US) 1990-07-17 US disclosed
US-4938881-A POLYOLEFIN REACTED WITH MALEIC ANHYDRIDE AND POLYAMINE, METAL SALT OF ORGANIC DITHIOPHOSPHORIC ACID THE LUBRIZOL CORPORATION (US) 1990-07-03 US disclosed
US-4904401-A BLEND OF OIL, POLYALKENYLSUCCINIMIDE AND METAL SALTS OF DIHYDROCARBYL PHOSPHORODITHIOIC ACIDS WITH ISOPROPYL OR SECONDARY BUTYL GROUPS THE LUBRIZOL CORPORATION (US) 1990-02-27 US disclosed
US-4740322-A Sulfur-containing compositions, and additive concentrates, lubricating oils, metal working lubricants and asphalt compositions containing same THE LUBRIZOL CORPORATION (US) 1988-04-26 US disclosed
EP-0232327-A1 SULFURIZED COMPOSITIONS, AND ADDITIVE CONCENTRATES, LUBRICATING COMPOSITIONS,METAL WORKING LUBRICANTS AND ASPHALT COMPOSITIONS CONTAINING SAME. LUBRIZOL CORP (US) 1987-08-19 EP disclosed
EP-0216207-A1 Thermoplastic resinous composition having excellent molding properties KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1987-04-01 EP disclosed
WO-1987000833-A1 SULFUR-CONTAINING COMPOSITIONS, AND ADDITIVE CONCENTRATES, LUBRICATING OILS, METAL WORKING LUBRICANTS AND ASPHALT COMPOSITIONS CONTAINING SAME THE LUBRIZOL CORPORATION (US) 1987-02-12 WO disclosed
US-4489194-A Carboxylic acylating agents substituted with olefin polymers of high/low molecular weight mono-olefins, derivatives thereof, and fuels and lubricants containing same THE LUBRIZOL CORPORATION (US) 1984-12-18 US disclosed