SCHEMBL5609353

SCHEMBL5609353

CC1(C)CC(=O)C(O)=C(O)C1

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.61
MAPT P10636 6/20 0.61
KDM4E B2RXH2 2/20 0.61
POLB P06746 1/20 0.59
GAA P10253 2/20 0.55
TDP2 O95551 1/20 0.48
SMAD3 P84022 1/20 0.48
HSD17B10 Q99714 1/20 0.48
KDM4C Q9H3R0 1/20 0.48
ATM Q13315 2/20 0.47
PTGES O14684 1/20 0.47
ALOX5 P09917 1/20 0.47
HTT P42858 1/20 0.43
TSHR P16473 1/20 0.42
TP53 P04637 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
LMNA P02545 1/20 0.41
MAOA P21397 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10216432 0.78 ALDH1A1 (0.59) ALDH1A1MAPTKDM4EPOLBGAA
SCHEMBL856999 0.78 ALDH1A1 (0.48) ALDH1A1MAPTKDM4EPOLBGAA
SCHEMBL13851163 0.76 ALDH1A1 (0.57) ALDH1A1MAPTKDM4EPOLBGAA
SCHEMBL17309024 0.76 ALDH1A1 (0.57) ALDH1A1MAPTKDM4EPOLBGAA
SCHEMBL2324941 0.74
SCHEMBL14707345 0.73 ALDH1A1 (0.53) ALDH1A1MAPTKDM4EPOLBGAA
SCHEMBL11609643 0.73 ALDH1A1 (0.69) ALDH1A1MAPTKDM4EPOLBGAA
SCHEMBL12267832 0.73 PTGES (0.64) ALDH1A1MAPTKDM4EPOLBGAA
SCHEMBL13966822 0.72 GAA (0.67) ALDH1A1MAPTKDM4EPOLBGAA
SCHEMBL5609472 0.70 ALDH1A1 (0.35) ALDH1A1MAPTKDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1735661-B1 THERMALLY DEVELOPABLE MATERIALS CONTAINING ORGANIC SILVER SALTS EASTMAN KODAK CO (US) 2007-09-05 EP disclosed
EP-1735661-A1 THERMALLY DEVELOPABLE MATERIALS CONTAINING ORGANIC SILVER SALTS EASTMAN KODAK COMPANY (US) 2006-12-27 EP disclosed
US-6977139-B2 Thermally developable materials containing organic silver salts with rod-like morphology and method of making and using EASTMAN KODAK COMPANY (US) 2005-12-20 US disclosed
WO-2005106581-A1 THERMALLY DEVELOPABLE MATERIALS CONTAINING ORGANIC SILVER SALTS EASTMAN KODAK COMPANY (US) 2005-11-10 WO disclosed
US-20050233268-A1 THERMALLY DEVELOPABLE MATERIALS CONTAINING ORGANIC SILVER SALTS WITH ROD-LIKE MORPHOLOGY AND METHOD OF MAKING AND USING EASTMAN KODAK COMPANY 2005-10-20 US disclosed
WO-2005050311-A1 STABILIZED HIGH-SPEED EMULSIONS AND PHOTOTHERMOGRAPHIC MATERIALS EASTMAN KODAK COMPANY (US) 2005-06-02 WO disclosed
US-20050106514-A1 Stabilized high-speed thermally developable emulsions and photothermographic materials EASTMAN KODAK COMPANY 2005-05-19 US disclosed
EP-1455225-A1 Thermally developable emulsions and materials containing heterocyclic disulfide compounds EASTMAN KODAK COMPANY (US) 2004-09-08 EP disclosed
US-6737227-B1 AND ASCORBIC ACID OR REDUCTONE REDUCING AGENTS; THERMOGRAPHIC AND PHOTOTHERMOGRAPHIC; INCREASED IMAGE DENSITY AND SHORTENED DEVELOPMENT TIME, DEVELOPMENT AT LOWER TEMPERATURES EASTMAN KODAK COMPANY 2004-05-18 US disclosed
EP-0692732-A1 Thermally processable image-recording material including reductone developing agent POLAROID CORPORATION (US) 1996-01-17 EP disclosed
US-5427905-A Thermally processable image-recording material including reductone developing agent POLAROID CORPORATION (US) 1995-06-27 US disclosed