SCHEMBL5609680

SCHEMBL5609680

CCCC(CC)c1c(C)cccc1C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CXCR5 P32302 1/20 0.59
ALDH1A1 P00352 5/20 0.46
KDM4E B2RXH2 3/20 0.46
HPGD P15428 2/20 0.46
HSD17B10 Q99714 2/20 0.46
MYC P01106 1/20 0.42
KMT2A Q03164 3/20 0.41
CYP3A4 P08684 2/20 0.41
CYP2C9 P11712 2/20 0.41
SLC6A2 P23975 1/20 0.40
SLC6A4 P31645 1/20 0.40
SLC6A3 Q01959 1/20 0.40
POLB P06746 2/20 0.40
MEN1 O00255 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
AKR1B10 O60218 1/20 0.39
TRPA1 O75762 1/20 0.39
ABCB11 O95342 1/20 0.39
DHFR P00374 1/20 0.39
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9998671 0.88 CXCR5 (0.49) CXCR5ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL6448195 0.83 CXCR5 (0.41) CXCR5ALDH1A1KDM4EKMT2ASLC6A3
SCHEMBL27594816 0.79 ALDH1A1 (0.46) ALDH1A1KDM4EHPGDHSD17B10MYC
SCHEMBL5923901 0.79 CXCR5 (0.48) CXCR5ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL10936470 0.79 ALDH1A1 (0.50) CXCR5ALDH1A1KDM4EKMT2ACYP3A4
SCHEMBL8147781 0.76 ALDH1A1 (0.50) CXCR5ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL6876901 0.76 POLB (0.44) CXCR5ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL409572 0.75 SLC37A4 (0.45) CXCR5ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL8291097 0.74 ALDH1A1 (0.57) ALDH1A1KDM4EHPGDHSD17B10MYC
SCHEMBL6444455 0.74 CXCR5 (0.36) CXCR5ALDH1A1KDM4EKMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1354887-B1 Ligands for metals and improved metal-catalyzed processes based thereon MASSACHUSETTS INST TECHNOLOGY (US) 2007-04-25 EP disclosed
EP-1097158-B1 LIGANDS FOR METALS AND METAL-CATALYZED PROCESSES MASSACHUSETTS INST TECHNOLOGY (US) 2006-01-25 EP disclosed
EP-1354887-A1 Ligands for metals and improved metal-catalyzed processes based thereon Massachusetts Insitute of Technology (US) 2003-10-22 EP disclosed
EP-1097158-A2 LIGANDS FOR METALS AND METAL-CATALYZED PROCESSES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2001-05-09 EP disclosed
WO-2000002887-A2 LIGANDS FOR METALS AND METAL-CATALYZED PROCESSES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2000-01-20 WO disclosed