SCHEMBL5609955

SCHEMBL5609955

[NH]c1ccc(-c2ccc([NH])c([NH])c2)cc1[NH]

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
AHR P35869 1/20 0.33
APP P05067 1/20 0.33
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8852690 0.71 APP (0.55) APPESR1ESR2
SCHEMBL49448 0.71 ALDH1A1 (0.48) TDP1ESR2
SCHEMBL8853374 0.71 APP (0.55) MEN1KMT2AAPPESR2
Ammonia Solution, Strong SCHEMBL28090402 0.59 ESR1 (0.57) ESR1ESR2
SCHEMBL5013872 0.55 ESR1 (0.71) TDP1ESR1ESR2
SCHEMBL239121 0.55 ESR1 (0.71) TDP1ESR1ESR2
SCHEMBL15902840 0.55 ESR1 (0.71) TDP1ESR1ESR2
SCHEMBL31039575 0.54 ESR1 (0.76) ESR1ESR2
SCHEMBL18260181 0.54 ESR1 (0.76) ESR1ESR2
SCHEMBL21616788 0.51

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1828210-A1 CHEMICAL COMPOSITIONS FOR AUTHENTICATABLE POLYMERS AND ARTICLES, AND AUTHENTICATION METHODS THEREOF General Electric Company (US) 2007-09-05 EP disclosed
WO-2006065541-A1 CHEMICAL COMPOSITIONS FOR AUTHENTICATABLE POLYMERS AND ARTICLES, AND AUTHENTICATION METHODS THEREOF GENERAL ELECTRIC COMPANY (US) 2006-06-22 WO disclosed