SCHEMBL49448

SCHEMBL49448

Cc1cc(-c2ccc([NH])c(C)c2)ccc1[NH]

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
CYP3A4 P08684 2/20 0.48
TSHR P16473 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
TP53 P04637 2/20 0.35
HSD17B1 P14061 2/20 0.35
HSD17B2 P37059 2/20 0.35
HPGD P15428 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
ESR2 Q92731 1/20 0.34
MCL1 Q07820 1/20 0.33
RXRB P28702 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL654886 0.77
SCHEMBL653334 0.72
SCHEMBL3610891 0.72
SCHEMBL6996374 0.72
SCHEMBL9479496 0.72
SCHEMBL5609955 0.71 MEN1 (0.33) TDP1ESR2
SCHEMBL29702110 0.71 ALDH1A1 (0.55) ALDH1A1CYP3A4TSHRTDP1TP53
SCHEMBL3084322 0.71 ALDH1A1 (0.55) ALDH1A1CYP3A4TSHRTDP1TP53
SCHEMBL9144961 0.70 ACHE (0.32) ALDH1A1CYP3A4TSHRTDP1TP53
SCHEMBL5390940 0.69 ALDH1A1 (0.52) ALDH1A1CYP3A4TSHRTDP1HSD17B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8229336-B2 Endless belt, cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2012-07-24 US disclosed
US-8131195-B2 Annular body for suppressing electrical discharge, annular body stretching device and image forming apparatus FUJI XEROX CO., LTD. (JP) 2012-03-06 US disclosed
US-20100247171-A1 ANNULAR BODY, CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2010-09-30 US disclosed
US-20090279924-A1 ANNULAR BODY, ANNULAR BODY STRETCHING DEVICE AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2009-11-12 US disclosed
US-7292813-B2 Intermediate transfer belt, production method for the same, and image forming device provided with the same FUJI XEROX CO., LTD. (JP) 2007-11-06 US disclosed
US-20060045578-A1 Intermediate transfer belt, production method for the same, and image forming device provided with the same FUJI XEROX CO., LTD. (JP) 2006-03-02 US disclosed