Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.65 |
| ▸ | LMNA | P02545 | 5/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | STAT3 | P40763 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 2/20 | 0.54 |
| ▸ | DRD4 | P21917 | 2/20 | 0.54 |
| ▸ | DRD3 | P35462 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30058168 | 1.00 | TDP1 (0.70) | TDP1SMN1; SMN2LMNATSHRALOX15 | |
| SCHEMBL14740042 | 0.98 | TDP1 (0.68) | TDP1SMN1; SMN2LMNATSHRALOX15 | |
| SCHEMBL5888624 | 0.98 | TDP1 (0.68) | TDP1SMN1; SMN2LMNATSHRALOX15 | |
| SCHEMBL5610799 | 0.98 | TDP1 (0.68) | TDP1SMN1; SMN2LMNATSHRALOX15 | |
| SCHEMBL825505 | 0.95 | TDP1 (0.72) | TDP1SMN1; SMN2LMNATSHRALOX15 | |
| SCHEMBL3161153 | 0.91 | TDP1 (0.84) | TDP1SMN1; SMN2LMNATSHRALOX15 | |
| SCHEMBL9814241 | 0.89 | TDP1 (0.81) | TDP1SMN1; SMN2LMNATSHRALOX15 | |
| SCHEMBL352046 | 0.89 | TDP1 (0.81) | TDP1SMN1; SMN2LMNATSHRALOX15 | |
| Ammonia Solution, Strong SCHEMBL7100443 | 0.89 | TDP1 (0.81) | TDP1SMN1; SMN2LMNATSHRALOX15 | |
| SCHEMBL353009 | 0.89 | TDP1 (0.81) | TDP1SMN1; SMN2LMNATSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445533-B2 | Andrographolide derivatives to treat viral infections | CORNELL RESEARCH FOUNDATION, INC. (US) | 2013-05-21 | — | — | US | disclosed |
| CN-102977321-A | compound for solar cell electrolyte, preparation method thereof, electrolyte containing compound and solar cell | EVERLIGHT CHEM IND CORP | 2013-03-20 | — | — | CN | disclosed |
| US-20130056075-A1 | COMPOUNDS FOR USE IN ELECTROLYTE FOR SOLAR CELL, METHOD FOR PREPARING THE SAME, AND ELECTROLYTE AND SOLAR CELL HAVING THE SAME | EVERLIGHT USA, INC. (US) | 2013-03-07 | — | — | US | disclosed |
| US-20130056075-A1 | COMPOUNDS FOR USE IN ELECTROLYTE FOR SOLAR CELL, METHOD FOR PREPARING THE SAME, AND ELECTROLYTE AND SOLAR CELL HAVING THE SAME | EVERLIGHT USA, INC. (US) | 2013-03-07 | — | — | US | disclosed |
| US-20130056075-A1 | COMPOUNDS FOR USE IN ELECTROLYTE FOR SOLAR CELL, METHOD FOR PREPARING THE SAME, AND ELECTROLYTE AND SOLAR CELL HAVING THE SAME | EVERLIGHT USA, INC. (US) | 2013-03-07 | — | — | US | disclosed |
| EP-1817024-A2 | ANDROGRAPHOLIDE DERIVATIVES TO TREAT VIRAL INFECTIONS | CORNELL RESEARCH FOUNDATION, INC. (US) | 2007-08-15 | — | — | EP | disclosed |
| US-20060223785-A1 | Andrographolide derivatives to treat viral infections | CORNELL RESEARCH FOUNDATION, INC. | 2006-10-05 | — | — | US | disclosed |
| WO-2006101538-A2 | ANDROGRAPHOLIDE DERIVATIVES TO TREAT VIRAL INFECTIONS | CORNELL RESEARCH FOUNDATION, INC. (US) | 2006-09-28 | — | — | WO | disclosed |
| US-20020128208-A1 | Nonpeptide agonists and antagonists of vasopressin receptors | EMORY UNIVERSITY | 2002-09-12 | — | — | US | disclosed |
| WO-2002047679-A2 | NONPEPTIDE AGONISTS AND ANTAGONISTS OF VASOPRESSIN RECEPTORS | EMORY UNIVERSITY (US) | 2002-06-20 | — | — | WO | disclosed |
| US-4377578-A | ANTIANAPHYLACTIC AGENTS, ANTIHISTAMINES | JANSSEN PHARMACEUTICA, N.V. (BE) | 1983-03-22 | — | — | US | disclosed |
| US-4250176-A | BENZIMIDAZOLE-2-ONE, BENZOTHIAZOL-2-ONE, OR BENZOXAZOL-2-ONE SUBSTITUTIONS, ANTIANAPHALACTIC AGENTS, ANTIHISTAMINES | JANSSEN PHARMACEUTICA N.V. (BE) | 1981-02-10 | — | — | US | disclosed |
| US-4200641-A | ANTIANAPHYLACTIC AGENTS, ANTIHISTAMINES | JANSSEN PHARMACEUTICA, N.V. (BE) | 1980-04-29 | — | — | US | disclosed |
| US-4175129-A | Antiemetic 1-(benzoxazolylalkyl)-piperidine derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1979-11-20 | — | — | US | disclosed |
| US-4160836-A | Antiemetic 1-(benzothiazolylalkyl)piperidine derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1979-07-10 | — | — | US | disclosed |
| US-4126687-A | ANTIEMETIC, 1-(BENZIMIDAZOLYL-ALKYL)-PIPERIDINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1978-11-21 | — | — | US | disclosed |
| US-4126688-A | ANTIEMETIC 1-(BENZOTRIAZOLYL-ALKYL)-PIPERIDINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1978-11-21 | — | — | US | disclosed |
| US-4110333-A | ANTIEMETIC INTERMEDIATES | JANSSEN PHARMACEUTICA N.V. (BE) | 1978-08-29 | — | — | US | disclosed |
| US-4066772-A | ANTIEMETICS | JANSSEN PHARMACEUTICA N.V. (BE) | 1978-01-03 | — | — | US | disclosed |
| US-4035369-A | 1-Benzazolylalkyl-4-substituted-piperidines | JANSSEN PHARMACEUTICA N.V. (BE) | 1977-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130056075-A1 | COMPOUNDS FOR USE IN ELECTROLYTE FOR SOLAR CELL, METHOD FOR PREPARING THE SAME, AND ELECTROLYTE AND SOLAR CELL HAVING THE SAME | HCN2, SCNN1A, HCN1 | TDP1 4412/4885SMN1; SMN2 3648/4885LMNA 494/4885 |
| US-20060223785-A1 | Andrographolide derivatives to treat viral infections | HAVCR2, MAVS, EIF2AK2 | TDP1 2239/4885SMN1; SMN2 3651/4885LMNA 2482/4885 |
| US-20020128208-A1 | Nonpeptide agonists and antagonists of vasopressin receptors | AVPR1A, AVPR2, AVPR1B | TDP1 3328/4885SMN1; SMN2 4469/4885LMNA 3740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.