Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ACR | P10323 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | MELK | Q14680 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5611054 | 1.00 | ALDH1A1 (0.37) | ALDH1A1ELANETNKSTP53DGAT1 | |
| SCHEMBL14370497 | 0.91 | ALDH1A1 (0.37) | ALDH1A1DGAT1KDM4EHSD17B10HPGD | |
| SCHEMBL14542193 | 0.86 | ELANE (0.34) | ALDH1A1ELANETNKSTP53POLB | |
| SCHEMBL14371514 | 0.85 | ELANE (0.36) | ALDH1A1ELANETNKSTP53POLB | |
| SCHEMBL5610868 | 0.85 | ALDH1A1 (0.40) | ALDH1A1TP53POLBCYP2C19KDM4E | |
| SCHEMBL5610874 | 0.85 | ALDH1A1 (0.40) | ALDH1A1TP53POLBCYP2C19KDM4E | |
| SCHEMBL14371556 | 0.84 | ALDH1A1 (0.39) | ALDH1A1TNKSTP53POLBCYP2C19 | |
| SCHEMBL14370260 | 0.83 | ALDH1A1 (0.39) | ALDH1A1TNKSTP53DGAT1POLB | |
| SCHEMBL5611023 | 0.83 | TP53 (0.35) | ALDH1A1ELANETP53DGAT1POLB | |
| SCHEMBL5611015 | 0.83 | TP53 (0.35) | ALDH1A1ELANETP53DGAT1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007147794-A1 | FURAN DERIVATIVES AND THEIR USE AS ANTIVIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-12-27 | — | — | WO | disclosed |
| WO-2007147794-A1 | FURAN DERIVATIVES AND THEIR USE AS ANTIVIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-12-27 | — | — | WO | disclosed |