Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5611015 | 1.00 | TP53 (0.35) | TP53RXFP1ALDH1A1HPGDKDM4E | |
| SCHEMBL5599403 | 0.92 | ALDH1A1 (0.35) | ALDH1A1DGAT1 | |
| SCHEMBL5599399 | 0.92 | ALDH1A1 (0.35) | ALDH1A1DGAT1 | |
| SCHEMBL14370493 | 0.86 | HPGD (0.36) | TP53RXFP1ALDH1A1HPGDKDM4E | |
| SCHEMBL14542365 | 0.84 | MAPK1 (0.36) | TP53RXFP1ALDH1A1HPGDKDM4E | |
| SCHEMBL14370459 | 0.83 | HPGD (0.34) | TP53RXFP1ALDH1A1HPGDKDM4E | |
| SCHEMBL5611054 | 0.83 | ALDH1A1 (0.37) | TP53ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL5611052 | 0.83 | ALDH1A1 (0.37) | TP53ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL14371556 | 0.83 | ALDH1A1 (0.39) | TP53ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL5610874 | 0.82 | ALDH1A1 (0.40) | TP53RXFP1ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007147794-A1 | FURAN DERIVATIVES AND THEIR USE AS ANTIVIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-12-27 | — | — | WO | disclosed |