SCHEMBL5611222

SCHEMBL5611222

CCOC(=O)C(CCBr)(CCBr)C(=O)OCC

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.57
KMT2A Q03164 3/20 0.57
ALDH1A1 P00352 4/20 0.44
TRPA1 O75762 1/20 0.44
LMNA P02545 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
CYP4F2 P78329 2/20 0.41
CYP4A11 Q02928 2/20 0.41
PKM P14618 2/20 0.41
THRB P10828 1/20 0.41
HTT P42858 1/20 0.40
HSD17B10 Q99714 1/20 0.39
KDM4E B2RXH2 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.37
ALOX15 P16050 1/20 0.37
MGAM O43451 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23388903 0.91 MEN1 (0.48) MEN1KMT2AALDH1A1TRPA1LMNA
SCHEMBL722151 0.87 MEN1 (0.53) MEN1KMT2AALDH1A1TRPA1LMNA
SCHEMBL21359810 0.83 MEN1 (0.42) MEN1KMT2AALDH1A1TRPA1LMNA
SCHEMBL5854543 0.83 MEN1 (0.42) MEN1KMT2AALDH1A1TRPA1LMNA
SCHEMBL4952112 0.82 ALDH1A1 (0.44) MEN1KMT2AALDH1A1TRPA1LMNA
SCHEMBL2353115 0.81 MEN1 (0.61) MEN1KMT2AALDH1A1LMNACYP1A2
SCHEMBL5611308 0.81 MEN1 (0.50) MEN1KMT2AALDH1A1TRPA1LMNA
SCHEMBL15910244 0.80 MMP8 (0.46) MEN1KMT2AALDH1A1TRPA1LMNA
SCHEMBL1398455 0.80 CYP4F2 (0.58) MEN1KMT2AALDH1A1TRPA1LMNA
SCHEMBL11680633 0.79 MEN1 (0.46) MEN1KMT2AALDH1A1TRPA1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10364304-B2 Method for producing solid catalyst component for olefin polymerization, catalyst for olefin polymerization, and method for producing olefin polymer TOHO TITANIUM CO., LTD. (JP) 2019-07-30 US disclosed
EP-1533322-B1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST TOHO TITANIUM CO LTD (JP) 2019-05-01 EP disclosed
US-20140206827-A1 METHOD FOR PRODUCING SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST FOR OLEFIN POLYMERIZATION, AND METHOD FOR PRODUCING OLEFIN POLYMER TOHO TITANIUM CO., LTD. (JP) 2014-07-24 US disclosed
US-7208435-B2 Solid catalyst component for olefin polymerization and catalyst TOHO CATALYST CO., LTD. (JP) 2007-04-24 US disclosed
US-20050227856-A1 Solid catalyst component for olefin polymerization and catalyst TOHO CATALYST CO., LTD. (JP) 2005-10-13 US disclosed
EP-1533322-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST Toho Catalyst Co., Ltd. (JP) 2005-05-25 EP disclosed