Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5611346 | 1.00 | TP53 (0.33) | TP53FFAR3LCKFYN | |
| SCHEMBL9860309 | 1.00 | TP53 (0.33) | TP53FFAR3LCKFYN | |
| SCHEMBL305018 | 0.97 | TP53 (0.32) | TP53FFAR3LCKFYN | |
| SCHEMBL305020 | 0.97 | TP53 (0.32) | TP53FFAR3LCKFYN | |
| SCHEMBL13923758 | 0.86 | TP53 (0.32) | TP53FFAR3LCKFYN | |
| SCHEMBL125330 | 0.81 | TP53 (0.41) | TP53FFAR3LCKFYN | |
| SCHEMBL126750 | 0.81 | TP53 (0.41) | TP53FFAR3LCKFYN | |
| SCHEMBL125331 | 0.81 | TP53 (0.41) | TP53FFAR3LCKFYN | |
| SCHEMBL14584344 | 0.79 | FFAR3 (0.35) | TP53FFAR3LCKFYN | |
| SCHEMBL304298 | 0.78 | TP53 (0.39) | TP53FFAR3LCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160151322-A1 | METALLO-B-LACTAMASE INHIBITORS | MEIJI SEIKA KAISHA (JP) | 2016-06-02 | — | — | US | disclosed |
| US-9260375-B2 | Metallo-β-lactamase inhibitors | MEIJI SEIKA KAISHA, LTD. (JP) | 2016-02-16 | — | — | US | disclosed |
| US-9115079-B2 | NDM inhibitor | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2015-08-25 | — | — | US | disclosed |
| US-20140221330-A1 | NDM INHIBITOR | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2014-08-07 | — | — | US | disclosed |
| WO-2013015388-A1 | NDM INHIBITOR | Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 (JP) | 2013-01-31 | — | — | WO | disclosed |
| US-8093294-B2 | Bacterial infections; effective for recovering the activities of beta-lactam antibiotics; 2-ethyl-3-methylmaleic acid dimethyl ester; maleic acid derivatives and/or dihydrofuranyl derivatives | MEIJI SEIKA KAISHA, LTD. (JP) | 2012-01-10 | — | — | US | disclosed |
| US-20080090825-A1 | Metallo-beta-lactamase inhibitors | MEIJI SEIKA KAISHA, LTD. (JP) | 2008-04-17 | — | — | US | disclosed |
| US-7208435-B2 | Solid catalyst component for olefin polymerization and catalyst | TOHO CATALYST CO., LTD. (JP) | 2007-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080090825-A1 | Metallo-beta-lactamase inhibitors | ME1, MGAM, GAA | TP53 4128/4885FFAR3 4843/4885LCK 4288/4885 |
| US-20140221330-A1 | NDM INHIBITOR | MGAM, NQO1, NQO2 | TP53 4395/4885FFAR3 4695/4885LCK 4645/4885 |
| US-20160151322-A1 | METALLO-B-LACTAMASE INHIBITORS | ME1, MGAM, MANBA | TP53 4221/4885FFAR3 4849/4885LCK 4378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.