Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NAAA | Q02083 | 6/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9364395 | 1.00 | TSHR (0.42) | TSHRNAAAEPHX2BCHEHCAR2 | |
| SCHEMBL28166491 | 0.84 | TSHR (0.44) | TSHRNAAAEPHX2HCAR2RAD52 | |
| SCHEMBL9359719 | 0.83 | ALDH1A1 (0.43) | NPSR1 | |
| SCHEMBL9359717 | 0.83 | ALDH1A1 (0.43) | NPSR1 | |
| SCHEMBL27619484 | 0.82 | HCAR2 (0.41) | TSHRNAAAEPHX2HCAR2 | |
| SCHEMBL5612679 | 0.82 | ATM (0.46) | TSHRNAAAEPHX2HCAR2NPSR1 | |
| SCHEMBL5612673 | 0.82 | ATM (0.46) | TSHRNAAAEPHX2HCAR2NPSR1 | |
| SCHEMBL10010171 | 0.78 | TSHR (0.50) | TSHRNAAAEPHX2RAD52NPSR1 | |
| SCHEMBL10011297 | 0.78 | TSHR (0.50) | TSHRNAAAEPHX2RAD52NPSR1 | |
| SCHEMBL10010175 | 0.78 | TSHR (0.50) | TSHRNAAAEPHX2RAD52NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393713-B1 | Process for the preparation of N-substituted maleimides | TOSOH CORP (JP) | 1994-06-29 | — | — | EP | disclosed |
| US-5087705-A | Heating N-substituted maleamic acid monoester in presence of acid catalyst | SHIN-DAIKYOWA PETROCHEMICAL CO., LTD. (JP) | 1992-02-11 | — | — | US | disclosed |
| EP-0393713-A1 | Process for the preparation of N-substituted maleimides | Tosoh Corporation (JP) | 1990-10-24 | — | — | EP | disclosed |