Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 13/20 | 0.38 |
| ▸ | HTR2A | P28223 | 11/20 | 0.38 |
| ▸ | HTR2B | P41595 | 8/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593821 | 0.83 | HTR2A (0.38) | HTR2CHTR2AHTR2B | |
| SCHEMBL5613036 | 0.81 | HTR2A (0.34) | HTR2CHTR2AHTR2B | |
| SCHEMBL5612907 | 0.80 | — | — | |
| SCHEMBL5613118 | 0.78 | TXNRD1 (0.33) | — | |
| SCHEMBL2080687 | 0.78 | HTR2C (0.57) | HTR2CHTR2AHTR2B | |
| SCHEMBL2077241 | 0.78 | HTR2C (0.57) | HTR2CHTR2AHTR2B | |
| SCHEMBL2080121 | 0.78 | HTR2C (0.57) | HTR2CHTR2AHTR2B | |
| SCHEMBL5612794 | 0.74 | — | — | |
| SCHEMBL5613205 | 0.72 | DRD2 (0.43) | HTR2CHTR2AHTR2B | |
| SCHEMBL2078422 | 0.72 | HTR2C (0.38) | HTR2CHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007140213-A1 | PYRIDOAZEPINE DERIVATIVES | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2007-12-06 | — | — | WO | disclosed |