SCHEMBL5612935

SCHEMBL5612935

Cc1nc2c(N)nc[nH]c-2nc1=O

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GDA Q9Y2T3 2/20 0.34
HRH2 P25021 1/20 0.33
HRH1 P35367 1/20 0.33
HRH4 Q9H3N8 1/20 0.33
HRH3 Q9Y5N1 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
KDM4E B2RXH2 1/20 0.32
GLA P06280 1/20 0.32
GAA P10253 1/20 0.32
PDPK1 O15530 2/20 0.31
PNP P00491 1/20 0.31
LMNA P02545 1/20 0.30
CYP1A2 P05177 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8720043 0.74 KDM4E (0.43) KDM4EGLAGAAMAPT
SCHEMBL3622613 0.71 ALDH1A1 (0.40)
SCHEMBL5612970 0.71 GDA (0.36) GDAKDM4EGLAGAAPDPK1
SCHEMBL21121885 0.71 GDA (0.34) GDAPDPK1LMNA
SCHEMBL5634577 0.66
SCHEMBL26049473 0.63
Adenine SCHEMBL5543734 0.63 PI4KA (0.42) GDATDP1KDM4EPDPK1LMNA
SCHEMBL3036602 0.59
SCHEMBL19493860 0.59
SCHEMBL5886967 0.58 PDE3B (0.35) GAAPDPK1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070238096-A1 Hybrid energy transfer for nucleic acid detection THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2007-10-11 US claimed
WO-2007103558-A2 HYBRID ENERGY TRANSFER FOR NUCLEIC ACID DETECTION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2007-09-13 WO claimed
US-20070238096-A1 Hybrid energy transfer for nucleic acid detection THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2007-10-11 US disclosed
WO-2007103558-A2 HYBRID ENERGY TRANSFER FOR NUCLEIC ACID DETECTION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2007-09-13 WO disclosed