Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TPMT | P51580 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.48 |
| ▸ | ANPEP | P15144 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31192242 | 0.81 | TSHR (0.60) | TSHRTP53ALDH1A1TPMTSMN1; SMN2 | |
| SCHEMBL372015 | 0.81 | TSHR (0.60) | TSHRTP53ALDH1A1TPMTSMN1; SMN2 | |
| SCHEMBL105270 | 0.81 | RXRA (0.62) | TSHRTP53ALDH1A1SMN1; SMN2KMT2A | |
| Terephthalic Acid SCHEMBL23071346 | 0.80 | TSHR (0.75) | TSHRTP53ALDH1A1TPMTSMN1; SMN2 | |
| Terephthalic Acid SCHEMBL23069370 | 0.80 | TSHR (0.75) | TSHRTP53ALDH1A1TPMTSMN1; SMN2 | |
| Terephthalic Acid SCHEMBL28393368 | 0.80 | TSHR (0.75) | TSHRTP53ALDH1A1TPMTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7667894 | 0.79 | RXRA (0.61) | TSHRTP53ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL9185162 | 0.79 | RXRA (0.61) | TSHRTP53ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL6912492 | 0.79 | TSHR (0.57) | TSHRTP53ALDH1A1TPMTSMN1; SMN2 | |
| SCHEMBL6911963 | 0.79 | TSHR (0.57) | TSHRTP53ALDH1A1TPMTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070270521-A1 | Transition metal compound, polymerization-initiator system comprising the same, and process for producing polymer | SUMITOMO CHEMICAL COMPANY, LIMITED | 2007-11-22 | — | — | US | disclosed |
| CN-101024659-A | Transition metal compound, polymerization initiator system including same and polymer production method | SUMITOMO CHEMICAL CO (JP) | 2007-08-29 | — | — | CN | disclosed |
| EP-1368381-B1 | 2-ALKYLATED-CYCLODEXTRIN DERIVATIVES: REVERSAL AGENTS FOR DRUG-INDUCED NEUROMUSCULAR BLOCK | AKZO NOBEL NV (NL) | 2006-05-03 | — | — | EP | disclosed |
| US-7026304-B2 | 2-alkylated-cyclodextrin derivatives: reversal agents for drug-induced neuromuscular block | AKZO NOBEL N.V. (NL) | 2006-04-11 | — | — | US | disclosed |
| US-20040106575-A1 | 2-Alkylated-cyclodextrin derivatives: reversal agents for drug-induced neuromuscular block | MERCK SHARP & DOHME B.V. (NL) | 2004-06-03 | — | — | US | disclosed |
| EP-1368381-A1 | 2-ALKYLATED-CYCLODEXTRIN DERIVATIVES: REVERSAL AGENTS FOR DRUG-INDUCED NEUROMUSCULAR BLOCK | Akzo Nobel N.V. (NL) | 2003-12-10 | — | — | EP | disclosed |
| WO-2002064635-A1 | 2-ALKYLATED-CYCLODEXTRIN DERIVATIVES: REVERSAL AGENTS FOR DRUG-INDUCED NEUROMUSCULAR BLOCK | AKZO NOBEL N.V. (NL) | 2002-08-22 | — | — | WO | disclosed |
| US-4554360-A | DIARYLIODONIUM SALT, IODOARENE, COUPLING | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1985-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070270521-A1 | Transition metal compound, polymerization-initiator system comprising the same, and process for producing polymer | CARM1, CPN1, CCNT1 | TSHR 4291/4885TP53 2689/4885ALDH1A1 1585/4885 |
| US-20040106575-A1 | 2-Alkylated-cyclodextrin derivatives: reversal agents for drug-induced neuromuscular block | SCN1B, SCN2B, CHRNB1 | TSHR 3020/4885TP53 4871/4885ALDH1A1 3591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.