Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | DAO | P14920 | 1/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 5/20 | 0.45 |
| ▸ | CES1 | P23141 | 5/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | CTSG | P08311 | 1/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL27642021 | 0.95 | DAO (0.47) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL27565744 | 0.93 | DAO (0.48) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL1081413 | 0.89 | DAO (0.48) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL27504747 | 0.89 | DAO (0.48) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL14956351 | 0.88 | LMNA (0.50) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL27522794 | 0.85 | TSHR (0.52) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL2020361 | 0.85 | TSHR (0.56) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL11508647 | 0.85 | TSHR (0.56) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL18918947 | 0.85 | TSHR (0.56) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL28679430 | 0.85 | TSHR (0.56) | TSHRDAONAPRTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290623-A | Polypropylene and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-118290624-A | Polypropylene and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-118290625-A | Polypropylene and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-117924549-A | Ziegler-Natta catalyst component, process for preparing the same, olefin polymerization catalyst and process for polymerizing olefin | 中国石油化工股份有限公司 | 2024-04-26 | — | — | CN | claimed |
| CN-117756970-A | Catalyst for butene-1 polymerization and application thereof | 中国石油化工股份有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-114437264-B | Low-VOC low-odor polypropylene resin and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-114456289-B | Titanium-containing catalyst, catalyst for olefin polymerization, preparation method and application thereof | 中国石油化工股份有限公司 | 2024-02-13 | — | — | CN | claimed |
| CN-114456288-B | Titanium-containing catalyst, catalyst for olefin polymerization reaction, preparation method and application thereof | 中国石油化工股份有限公司 | 2024-02-13 | — | — | CN | claimed |
| CN-116769090-A | Preparation method of butene-1 polymer | 中国石油化工股份有限公司 | 2023-09-19 | — | — | CN | claimed |
| CN-116769088-A | Preparation method of high isotactic polybutene-1 | 中国石油化工股份有限公司 | 2023-09-19 | — | — | CN | claimed |
| CN-109096415-B | Olefin polymerization catalyst component, process for producing the same, olefin polymerization catalyst, and process for producing olefin polymer | 中国石油化工股份有限公司 | 2021-03-16 | — | — | CN | claimed |
| CN-106608937-B | Catalytic component and its preparation method and application for olefinic polymerization | 中国石油化工股份有限公司 | 2019-04-19 | — | — | CN | claimed |
| CN-106608933-B | Catalytic component and its preparation method and application for olefinic polymerization | 中国石油化工股份有限公司 | 2019-03-26 | — | — | CN | claimed |
| CN-106317274-B | Prepare catalytic component of fiber polyolefin and its preparation method and application and catalyst system and application and olefine polymerizing process | 中国石油化工股份有限公司 | 2018-12-28 | — | — | CN | claimed |
| CN-106317275-B | Prepare catalytic component of fiber polyolefin and its preparation method and application and catalyst system and application and olefine polymerizing process | 中国石油化工股份有限公司 | 2018-12-28 | — | — | CN | claimed |
| CN-109096415-A | The preparation method of catalyst component for olefin polymerization and preparation method thereof and olefin polymerization catalysis and olefin polymer | 中国石油化工股份有限公司 | 2018-12-28 | — | — | CN | claimed |
| EP-3059264-B1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, PREPARATION METHOD THEREOF, AND CATALYST COMPRISING SAME | CHINA PETROLEUM & CHEM CORP (CN) | 2018-12-26 | — | — | EP | claimed |
| EP-1472293-B1 | SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF | CHINA PETROLEUM & CHEM CORP (CN) | 2017-04-26 | — | — | EP | claimed |
| US-20160264694-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, PREPARATION METHOD THEREOF, AND CATALYST COMPRISING SAME | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2016-09-15 | — | — | US | claimed |
| EP-3059264-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, PREPARATION METHOD THEREOF, AND CATALYST COMPRISING SAME | China Petroleum&Chemical Corporation (CN) | 2016-08-24 | — | — | EP | claimed |