Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | DAO | P14920 | 1/20 | 0.56 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.56 |
| ▸ | CES1 | P23141 | 4/20 | 0.48 |
| ▸ | CES2 | O00748 | 3/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL11508647 | 1.00 | TSHR (0.56) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL18918947 | 1.00 | TSHR (0.56) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL2160981 | 0.93 | TSHR (0.48) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL235922 | 0.89 | TSHR (0.52) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL11436196 | 0.89 | TSHR (0.52) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL505771 | 0.89 | TSHR (0.52) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL28094912 | 0.88 | DAO (0.44) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL561340 | 0.85 | TSHR (0.52) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL570916 | 0.83 | DAO (0.50) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL27530468 | 0.83 | TSHR (0.50) | TSHRDAONAPRTCES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 301 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12390971-B2 | Process and system for blending a plasticizer with a polysaccharide ester polymer | CELANESE INTERNATIONAL CORPORATION (US) | 2025-08-19 | — | — | US | claimed |
| EP-4558557-A1 | COMPOSITION CONTAINING CELLULOSE ESTER POLYMER WITH ENHANCED MELT STRENGTH AGENT | Celanese International Corporation (US) | 2025-05-28 | — | — | EP | claimed |
| CN-119894971-A | Compositions containing cellulose ester polymers and enhanced melt strength agents | 国际人造丝公司 | 2025-04-25 | — | — | CN | claimed |
| WO-2023137146-A9 | CELLULOSE ESTER COMPOSITION AND PROCESS FOR PRODUCING ARTICLES THEREFROM | CELANESE INTERNATIONAL CORPORATION (US) | 2024-05-23 | — | — | WO | claimed |
| US-20240026122-A1 | Composition Containing Cellulose Ester Polymer With Enhanced Melt Strength Agent | CELANESE INTERNATIONAL CORPORATION | 2024-01-25 | — | — | US | claimed |
| WO-2024020193-A1 | BIO-BASED POLYMER COMPOSITION CONTAINING ODOR MASKING AGENT | CELANESE INTERNATIONAL CORPORATION (US) | 2024-01-25 | — | — | WO | claimed |
| WO-2024020195-A1 | COMPOSITION CONTAINING CELLULOSE ESTER POLYMER WITH ENHANCED MELT STRENGTH AGENT | CELANESE INTERNATIONAL CORPORATION (US) | 2024-01-25 | — | — | WO | claimed |
| US-20240026130-A1 | Bio-Based Polymer Composition Containing Odor Masking Agent | CELANESE INT CORP (US) | 2024-01-25 | — | — | US | claimed |
| WO-2023244729-A1 | CELLULOSE ESTER POLYMER PRODUCT WITH INCREASED MELT FLOW PROPERTIES AND REFLECTANCE | CELANESE INTERNATIONAL CORPORATION (US) | 2023-12-21 | — | — | WO | claimed |
| EP-4258858-A1 | FOAM FORMED FROM CELLULOSE ESTER COMPOSITION | Celanese International Corporation (US) | 2023-10-18 | — | — | EP | claimed |
| US-RE32334-E | Molding resins | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-01-20 | — | — | US | claimed |
| EP-0157426-A2 | Flame retardant thermoplastic polyester molding composition | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-10-09 | — | — | EP | claimed |
| US-4366273-A | Polyester composition with mixed metal ion nucleating agents | ALLIED CORPORATION (US) | 1982-12-28 | — | — | US | claimed |
| US-4352904-A | POLYETHYLENE TEREPHTHALATE; FILLER OR REINFORCEMENT; SODIUM OR POTASSIUM CARBOXYLATE; ESTER, KETONE, SULFONE, SULFOXIDE, NITRILE, OR AMIDE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-10-05 | — | — | US | claimed |
| US-4349503-A | CRYSTALLIZATION; SODIUM NITRITE AS A NUCLEATING AGENT | ALLIED CORPORATION (US) | 1982-09-14 | — | — | US | claimed |
| US-4303717-A | OXYALKYLATED ALCOHOL | COMMERCIAL DECAL, INC. (US) | 1981-12-01 | — | — | US | claimed |
| US-4259225-A | STORAGE STABILITY | DAINIPPON INK & CHEMICALS, INC. (JP) | 1981-03-31 | — | — | US | claimed |
| US-4172824-A | PLASTICIZER | EASTMAN KODAK COMPANY (US) | 1979-10-30 | — | — | US | claimed |
| US-4117182-A | ALIPHATIC OXYALKYLATED ALCOHOL, HEAT ACTIVATABLE ADHESIVE | COMMERCIAL DECAL, INC. (US) | 1978-09-26 | — | — | US | claimed |
| US-4068033-A | Heat-releasable decalcomanias and adhesive composition therefor | COMMERCIAL DECAL, INC. (US) | 1978-01-10 | — | — | US | claimed |