SCHEMBL56139

SCHEMBL56139

NC(CCP(=O)(O)O)C(=O)O

nearest known ligand 0.70

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GLUL P15104 1/20 0.70
GRM8 O00222 1/20 0.62
GRM6 O15303 1/20 0.62
GRM7 Q14831 1/20 0.62
GRM4 Q14833 1/20 0.62
BHMT Q93088 1/20 0.59
GCLC P48506 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31230376 1.00 GLUL (0.70) GLULGRM8GRM6GRM7GRM4
SCHEMBL1969235 1.00 GLUL (0.70) GLULGRM8GRM6GRM7GRM4
SCHEMBL12648443 1.00 GLUL (0.70) GLULGRM8GRM6GRM7GRM4
Hydrochloric Acid SCHEMBL8842420 0.98 GLUL (0.68) GLULGRM8GRM6GRM7GRM4
Water SCHEMBL21747433 0.98 GLUL (0.68) GLULGRM8GRM6GRM7GRM4
Water SCHEMBL21747423 0.98 GLUL (0.68) GLULGRM8GRM6GRM7GRM4
Water SCHEMBL21747432 0.98 GLUL (0.68) GLULGRM8GRM6GRM7GRM4
Methyl Alcohol SCHEMBL28474438 0.96 GLUL (0.66) GLULGRM8GRM6GRM7GRM4
D-Glutamate SCHEMBL6861834 0.90 GRM8 (0.69) GLULGRM8GRM6GRM7GRM4
Glutamic Acid SCHEMBL6861840 0.90 GRM8 (0.69) GLULGRM8GRM6GRM7GRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1427 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260103494-A1 GENE THERAPY TREATMENT UNIVERSITY OF SHEFFIELD (GB) 2026-04-16 US claimed
US-20260083744-A1 METHODS TO STRENGTHEN VISUAL PATHWAYS GEORGIA TECH RES INST (US) 2026-03-26 US claimed
EP-4712970-A2 COMPOUNDS FOR TREATING HEREDITARY SPASTIC PARAPLEGIA The Children's Medical Center Corporation (US) 2026-03-25 EP claimed
EP-4694882-A2 COMPOUNDS FOR TREATING RETT SYNDROME AND OTHER DISORDERS Unravel Biosciences, Inc. (US) 2026-02-18 EP claimed
EP-4601463-A1 GENE THERAPY TREATMENT University of Sheffield (GB) 2025-08-20 EP claimed
CN-120035379-A Gene therapy treatment 谢菲尔德大学 2025-05-23 CN claimed
WO-2024243015-A2 COMPOUNDS FOR TREATING HEREDITARY SPASTIC PARAPLEGIA THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2024-11-28 WO claimed
WO-2024215967-A2 COMPOUNDS FOR TREATING RETT SYNDROME AND OTHER DISORDERS UNRAVEL BIOSCIENCES, INC. (US) 2024-10-17 WO claimed
CN-118684620-A Betel nut alkaloid and preparation method and application thereof 暨南大学 2024-09-24 CN claimed
US-20240200050-A1 AMINOACYL TRANSFER RNA SYNTHETASES TRUSTEES OF TUFTS COLLEGE (US) 2024-06-20 US claimed
EP-0904777-A1 Use of an excitatory amino acids inhibitor in cosmetic or dermatological compositions for sensitive kin and composition obtained L'OREAL (FR) 1999-03-31 EP claimed
US-5873812-A REDUCING PROSTHETIC ORGAN AND TISSUE REJECTION; BINDING EXCESS ALDEHYDE FIXATIVE BY TREATMENT WITH AN AMINOCARBOXYLIC ACID IN ACIDIC MEDIUM SORIN BIOMEDICA CARDIO S.P.A. (IT) 1999-02-23 US claimed
EP-0845217-A1 Inhibiting undesirable taste in oral compositions THE PROCTER & GAMBLE COMPANY (US) 1998-06-03 EP claimed
EP-0795337-A2 A method of preparing biological implantation material SORIN BIOMEDICA CARDIO S.p.A. (IT) 1997-09-17 EP claimed
US-5500420-A Metabotropic glutamate receptor agonists in the treatment of cerebral ischemia CORNELL RESEARCH FOUNDATION, INC. (US) 1996-03-19 US claimed
WO-1995028081-A1 ADDRESSING BAIT AVERSION BY DISRUPTING ASSOCIATIVE LEARNING THE MEAT INDUSTRY RESEARCH INSTITUTE OF NEW ZEALAND INC. (NZ) 1995-10-26 WO claimed
US-5202257-A Pure DNA which is capable of hybridizing with receptor polynucleotides under mild conditions THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1993-04-13 US claimed
EP-0497884-A1 GLUTAMATE RECEPTOR COMPOSITIONS AND METHODS THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1992-08-12 EP claimed
WO-1991006648-A1 GLUTAMATE RECEPTOR COMPOSITIONS AND METHODS THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 1991-05-16 WO claimed
EP-0127429-B1 PROCESS FOR PREPARING OPTICALLY ACTIVE ((3-AMINO-3-CARBOXY)PROPYL-1) PHOSPHINIC ACID DERIVATIVES MEIJI SEIKA KAISHA LTD. (JP) 1989-04-19 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260083744-A1 METHODS TO STRENGTHEN VISUAL PATHWAYS GRM6, GRM3, GRM2 GLUL 544/4885GRM8 15/4885GRM6 1/4885
US-20260103494-A1 GENE THERAPY TREATMENT AP3B1, PAIP1, AP2B1 GLUL 3458/4885GRM8 2956/4885GRM6 2834/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.