Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 7/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5355490 | 0.77 | SLC6A2 (0.44) | SLC6A2SLC6A4LTA4HDPP4DPP9 | |
| SCHEMBL18828701 | 0.76 | LTA4H (0.59) | SLC6A2SLC6A4LTA4HYTHDC1OPRM1 | |
| SCHEMBL18987599 | 0.76 | YTHDC1 (0.48) | SLC6A2SLC6A4DPP4DPP9DPP7 | |
| SCHEMBL5357408 | 0.73 | SLC6A2 (0.39) | SLC6A2SLC6A4LTA4HDPP4DPP9 | |
| SCHEMBL28984093 | 0.72 | YTHDC1 (0.47) | SLC6A2SLC6A4DPP4DPP9DPP7 | |
| SCHEMBL30389942 | 0.72 | YTHDC1 (0.47) | SLC6A2SLC6A4DPP4DPP9DPP7 | |
| SCHEMBL3376962 | 0.72 | YTHDC1 (0.58) | SLC6A2SLC6A4DPP4DPP9DPP7 | |
| SCHEMBL17103499 | 0.71 | YTHDC1 (0.49) | SLC6A2SLC6A4YTHDC1OPRM1OPRK1 | |
| SCHEMBL17103497 | 0.71 | YTHDC1 (0.49) | SLC6A2SLC6A4YTHDC1OPRM1OPRK1 | |
| SCHEMBL30389917 | 0.71 | YTHDC1 (0.46) | SLC6A2SLC6A4DPP4DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831158-A1 | NOVEL CYCLOHEXANE DERIVATIVES | F. Hoffmann-Roche AG (CH) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006066779-A1 | NOVEL CYCLOHEXANE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2006-06-29 | — | — | WO | disclosed |