Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 12/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.37 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.36 |
| ▸ | ITGAL | P20701 | 1/20 | 0.36 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5615895 | 1.00 | GHSR (0.42) | GHSROPRM1ACESOS1ITGB2 | |
| SCHEMBL5616078 | 1.00 | GHSR (0.42) | GHSROPRM1ACESOS1ITGB2 | |
| SCHEMBL9391359 | 0.92 | GHSR (0.48) | GHSROPRM1ACEITGB2ICAM1 | |
| SCHEMBL5666463 | 0.92 | GHSR (0.51) | GHSROPRM1ACE | |
| SCHEMBL5615834 | 0.92 | GHSR (0.51) | GHSROPRM1ACE | |
| SCHEMBL9391345 | 0.92 | GHSR (0.51) | GHSROPRM1ACE | |
| SCHEMBL5616106 | 0.91 | GHSR (0.40) | GHSROPRM1SOS1TGM2MEN1 | |
| SCHEMBL5616251 | 0.86 | GHSR (0.38) | GHSROPRM1SOS1EPHA2TGM2 | |
| SCHEMBL5615780 | 0.83 | GHSR (0.48) | GHSROPRM1ACEKMT2A | |
| SCHEMBL9391064 | 0.81 | GHSR (0.50) | GHSROPRM1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781311-A2 | GROWTH-HORMONE SECRETAGOGUES | Elixir Pharmaceuticals, Inc. (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006023608-A2 | GROWTH-HORMONE SECRETAGOGUES | ELIXIR PHARMACEUTICALS, INC. (US) | 2006-03-02 | — | — | WO | disclosed |