Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 16/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5616106 | 0.92 | GHSR (0.40) | GHSROPRM1KMT2A | |
| SCHEMBL5615834 | 0.91 | GHSR (0.51) | GHSROPRM1ACE | |
| SCHEMBL5666463 | 0.91 | GHSR (0.51) | GHSROPRM1ACE | |
| SCHEMBL9391345 | 0.91 | GHSR (0.51) | GHSROPRM1ACE | |
| SCHEMBL5616251 | 0.86 | GHSR (0.38) | GHSROPRM1MAPTKMT2A | |
| SCHEMBL9391064 | 0.86 | GHSR (0.50) | GHSROPRM1ACE | |
| SCHEMBL5615895 | 0.83 | GHSR (0.42) | GHSROPRM1ACEKMT2A | |
| SCHEMBL5616078 | 0.83 | GHSR (0.42) | GHSROPRM1ACEKMT2A | |
| SCHEMBL9391359 | 0.83 | GHSR (0.48) | GHSROPRM1ACEKMT2A | |
| SCHEMBL5615528 | 0.83 | GHSR (0.42) | GHSROPRM1ACEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781311-A2 | GROWTH-HORMONE SECRETAGOGUES | Elixir Pharmaceuticals, Inc. (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006023608-A2 | GROWTH-HORMONE SECRETAGOGUES | ELIXIR PHARMACEUTICALS, INC. (US) | 2006-03-02 | — | — | WO | disclosed |