Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 3/20 | 0.49 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.49 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL482961 | 0.85 | CPB2 (0.44) | SLC1A2SLC1A1SLC1A3SLC7A5 | |
| SCHEMBL482963 | 0.85 | CPB2 (0.44) | SLC1A2SLC1A1SLC1A3SLC7A5 | |
| SCHEMBL29126191 | 0.84 | SLC1A2 (0.50) | SLC1A2SLC1A1SLC1A3SLC15A1CA2 | |
| SCHEMBL7864753 | 0.84 | SLC1A2 (0.50) | SLC1A2SLC1A1SLC1A3SLC15A1CA2 | |
| SCHEMBL9203696 | 0.80 | CA2 (0.50) | SLC1A2SLC1A1SLC1A3SLC15A1CA2 | |
| Bromide SCHEMBL9295134 | 0.79 | CA2 (0.49) | SLC1A2SLC1A1SLC1A3SLC15A1CA2 | |
| Bromide SCHEMBL9295139 | 0.79 | CA2 (0.49) | SLC1A2SLC1A1SLC1A3SLC15A1CA2 | |
| SCHEMBL5296286 | 0.76 | SLC1A2 (0.50) | SLC1A2SLC1A1SLC1A3SLC15A1CA2 | |
| SCHEMBL8666519 | 0.76 | SLC1A2 (0.50) | SLC1A2SLC1A1SLC1A3SLC15A1CA2 | |
| SCHEMBL7202198 | 0.76 | SLC1A2 (0.50) | SLC1A2SLC1A1SLC1A3SLC15A1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007016597-A2 | TARGETING TNF-ALPHA CONVERTING ENZYME (TACE)-DEPENDENT GROWTH FACTOR SHEDDING IN CANCER THERAPY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-02-08 | — | — | WO | disclosed |