Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL460145 | 0.84 | MAPT (0.33) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10344281 | 0.83 | ALDH1A1 (0.37) | ALDH1A1MAPT | |
| SCHEMBL10579900 | 0.83 | ALDH1A1 (0.37) | ALDH1A1MAPT | |
| SCHEMBL19022224 | 0.80 | CEL (0.34) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3902389 | 0.77 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL9418314 | 0.77 | CA1 (0.48) | ALDH1A1KMT2A | |
| SCHEMBL8815894 | 0.77 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL195524 | 0.77 | MAPT (0.33) | ALDH1A1MAPT | |
| SCHEMBL18984549 | 0.76 | KCNJ1 (0.33) | ALDH1A1MAPT | |
| Ethylene Glycol SCHEMBL487137 | 0.76 | MEN1 (0.31) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763526-A1 | 4,6-DISUBSTITUTED PYRIMIDINES AND THEIR USE AS PROTEIN KINASE INHIBITORS | Altana Pharma AG (DE) | 2007-03-21 | — | — | EP | disclosed |
| WO-2006000589-A1 | 4,6-DISUBSTITUTED PYRIMIDINES AND THEIR USE AS PROTEIN KINASE INHIBITORS | ALTANA PHARMA AG (DE) | 2006-01-05 | — | — | WO | disclosed |
| JP-2005088274-A | BIODEGRADABLE LAMINATED PAPER | UBE IND LTD | 2005-04-07 | — | — | JP | disclosed |