Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKB | Q96GD4 | 10/20 | 0.61 |
| ▸ | AURKA | O14965 | 10/20 | 0.61 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | STK4 | Q13043 | 1/20 | 0.37 |
| ▸ | STK3 | Q13188 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5594245 | 0.93 | AURKB (0.70) | AURKBAURKACHEK1KDR | |
| SCHEMBL5593800 | 0.91 | AURKB (0.70) | AURKBAURKACHEK1KDR | |
| SCHEMBL5594004 | 0.88 | AURKB (0.60) | AURKBAURKACHEK1KDRBRD4 | |
| SCHEMBL5594008 | 0.88 | AURKB (0.60) | AURKBAURKACHEK1KDRBRD4 | |
| SCHEMBL5594049 | 0.84 | AURKB (0.57) | AURKBAURKATDP1 | |
| SCHEMBL5594047 | 0.84 | AURKB (0.57) | AURKBAURKATDP1 | |
| SCHEMBL5593744 | 0.82 | AURKB (0.62) | AURKBAURKA | |
| SCHEMBL5593748 | 0.82 | AURKB (0.62) | AURKBAURKA | |
| SCHEMBL14539135 | 0.82 | AURKB (0.85) | AURKBAURKAKDR | |
| SCHEMBL5593867 | 0.81 | AURKB (0.56) | AURKBAURKACHEK1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058626-A1 | INDAZOLE COMPOUNDS | S*BIO PTE LTD (SG) | 2007-05-24 | — | — | WO | claimed |