Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKB | Q96GD4 | 9/20 | 0.56 |
| ▸ | AURKA | O14965 | 9/20 | 0.56 |
| ▸ | KDR | P35968 | 9/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593870 | 0.89 | AURKB (0.58) | AURKBAURKAKDRFGFR1CHEK1 | |
| SCHEMBL5594245 | 0.88 | AURKB (0.70) | AURKBAURKAKDRFGFR1CHEK1 | |
| SCHEMBL14539053 | 0.82 | AURKB (0.81) | AURKBAURKAKDRFGFR1 | |
| SCHEMBL5593800 | 0.81 | AURKB (0.70) | AURKBAURKAKDRCHEK1 | |
| SCHEMBL5616573 | 0.81 | AURKB (0.65) | AURKBAURKAKDRFGFR1CHEK1 | |
| SCHEMBL14538910 | 0.81 | AURKB (0.65) | AURKBAURKAKDRFGFR1CHEK1 | |
| SCHEMBL5616552 | 0.81 | AURKB (0.61) | AURKBAURKAKDRCHEK1 | |
| SCHEMBL14539154 | 0.77 | AURKB (0.54) | AURKBAURKAKDRFGFR1 | |
| SCHEMBL14539036 | 0.76 | AURKB (0.59) | AURKBAURKAKDRFGFR1 | |
| SCHEMBL5593696 | 0.76 | AURKB (0.59) | AURKBAURKAKDRFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058626-A1 | INDAZOLE COMPOUNDS | S*BIO PTE LTD (SG) | 2007-05-24 | — | — | WO | claimed |
| WO-2007058626-A1 | INDAZOLE COMPOUNDS | S*BIO PTE LTD (SG) | 2007-05-24 | — | — | WO | disclosed |