SCHEMBL561674

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2910293	0.94	LCK (0.39)	LCKGPR35ALOX15BACE1CYP3A4
	SCHEMBL2909590	0.90	KMT2A (0.42)	LCKALOX15PDE3BPDE3APDE4A
	SCHEMBL2908981	0.88	LCK (0.42)	LCKBACE1CYP3A4HPGDNQO2
	SCHEMBL1274217	0.84	LCK (0.38)	LCKALOX15NQO2ALDH1A1LMNA
	SCHEMBL2909941	0.83	NQO2 (0.45)	LCKBACE1CYP3A4HPGDNQO2
	SCHEMBL2909922	0.82	NQO2 (0.44)	LCKALOX15NQO2KDM4EMAPT
	SCHEMBL2907736	0.81	GPR35 (0.52)	GPR35ALOX15PDE3BPDE3APDE4A
	SCHEMBL2903468	0.80	NQO2 (0.45)	LCKBACE1CYP3A4HPGDNQO2
	SCHEMBL2911221	0.80	LCK (0.39)	LCKBACE1CYP3A4HPGDNQO2
	SCHEMBL2904873	0.78	NQO2 (0.48)	LCKNQO2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.