Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9616134 | 0.88 | KCNMA1 (0.55) | KCNMA1RAB9ANPSR1SMN1; SMN2KMT2A | |
| SCHEMBL20323971 | 0.88 | KCNMA1 (0.48) | KCNMA1RAB9ANPSR1TSHRRXFP1 | |
| SCHEMBL3906689 | 0.80 | KCNMA1 (0.63) | KCNMA1RAB9ANPSR1TSHRRXFP1 | |
| SCHEMBL8849556 | 0.78 | KCNMA1 (0.47) | KCNMA1RAB9ANPSR1TSHRSMN1; SMN2 | |
| SCHEMBL13093779 | 0.77 | KCNMA1 (0.55) | KCNMA1RAB9ANPSR1TSHRRXFP1 | |
| SCHEMBL18599169 | 0.77 | KCNMA1 (0.55) | KCNMA1RAB9ANPSR1TSHRRXFP1 | |
| SCHEMBL18780221 | 0.76 | KCNMA1 (0.58) | KCNMA1RAB9ANPSR1TSHRSMN1; SMN2 | |
| SCHEMBL2730923 | 0.75 | KCNMA1 (0.57) | KCNMA1RAB9ANPSR1KMT2AMAPT | |
| SCHEMBL1938292 | 0.75 | KCNMA1 (0.53) | KCNMA1RAB9ANPSR1TSHRRXFP1 | |
| SCHEMBL30049983 | 0.75 | KCNMA1 (0.53) | KCNMA1RAB9ANPSR1TSHRRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859835-A2 | Topical agent for dermatological use containing 4-hydroxyphenyl-alpha-D-glucopyranoside | PENTAPHARM Ltd. (CH) | 2007-11-28 | — | — | EP | claimed |