Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.42 |
| ▸ | CHRNG | P07510 | 1/20 | 0.42 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | CHRND | Q07001 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22613508 | 0.81 | ALDH1A1 (0.45) | SMN1; SMN2LMNAMEN1PABPC1KMT2A | |
| SCHEMBL2082178 | 0.79 | LMNA (0.42) | SMN1; SMN2LMNAMEN1PABPC1KMT2A | |
| SCHEMBL1932565 | 0.77 | TSHR (0.38) | SMN1; SMN2LMNAMEN1PABPC1KMT2A | |
| SCHEMBL3884112 | 0.77 | CYP19A1 (0.40) | SMN1; SMN2LMNAMEN1PABPC1KMT2A | |
| SCHEMBL2262224 | 0.77 | TSHR (0.38) | SMN1; SMN2LMNAMEN1PABPC1KMT2A | |
| SCHEMBL587682 | 0.77 | TAAR1 (0.42) | SMN1; SMN2LMNAMEN1PABPC1KMT2A | |
| SCHEMBL4588500 | 0.77 | ESR2 (0.41) | SMN1; SMN2LMNAMEN1PABPC1KMT2A | |
| SCHEMBL9047543 | 0.77 | TSHR (0.38) | SMN1; SMN2LMNAMEN1PABPC1KMT2A | |
| SCHEMBL2084415 | 0.77 | LMNA (0.54) | SMN1; SMN2LMNAMEN1PABPC1KMT2A | |
| SCHEMBL23951432 | 0.77 | SMN1; SMN2 (0.43) | SMN1; SMN2LMNAMEN1PABPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007057658-A1 | PALLADIUM CATALYSED HECK ARYLATION OR VINYLATION OF 1-SUBSTITUTED OLEFINS | THE UNIVERSITY OF LIVERPOOL (GB) | 2007-05-24 | — | — | WO | disclosed |
| WO-2007057658-A1 | PALLADIUM CATALYSED HECK ARYLATION OR VINYLATION OF 1-SUBSTITUTED OLEFINS | THE UNIVERSITY OF LIVERPOOL (GB) | 2007-05-24 | — | — | WO | disclosed |