Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4910223 | 0.83 | ALDH1A1 (0.50) | L3MBTL1ALDH1A1MAPTRAB9ACYP1A2 | |
| SCHEMBL4908140 | 0.78 | CYP3A4 (0.42) | LMNAALDH1A1SMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL7589137 | 0.77 | KDM4E (0.50) | LMNAALDH1A1SMN1; SMN2CYP19A1KDM4E | |
| SCHEMBL7590836 | 0.77 | KDM4E (0.50) | LMNAALDH1A1SMN1; SMN2CYP19A1KDM4E | |
| SCHEMBL2788882 | 0.77 | KDM4E (0.50) | LMNAALDH1A1SMN1; SMN2CYP19A1KDM4E | |
| SCHEMBL9114461 | 0.77 | NQO1 (0.64) | L3MBTL1LMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL31040269 | 0.76 | SMN1; SMN2 (0.41) | L3MBTL1LMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6920072 | 0.76 | MAPK1 (0.45) | LMNASMN1; SMN2CYP1A2CYP19A1KDM4E | |
| SCHEMBL4899497 | 0.76 | HTT (0.45) | LMNAALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL17865259 | 0.76 | CYP3A4 (0.42) | LMNAMAPTSMN1; SMN2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1755678-A2 | ACTIVE SUBSTANCE COMBINATION OF A CARBINOL COMPOUND AND AN OPIOID | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005097192-A2 | ACTIVE SUBSTANCE COMBINATION OF A CARBINOL COMPOUND AND AN OPIOID | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2005-10-20 | — | — | WO | disclosed |