Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.34 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4908140 | 0.84 | CYP3A4 (0.42) | LMNASMN1; SMN2IDO1KDM4EPRKDC | |
| SCHEMBL17847834 | 0.84 | CYP17A1 (0.44) | LMNASMN1; SMN2KDM4EPRKDCKCNH2 | |
| SCHEMBL2788882 | 0.84 | KDM4E (0.50) | LMNASMN1; SMN2KDM4ECYP19A1 | |
| SCHEMBL7590836 | 0.84 | KDM4E (0.50) | LMNASMN1; SMN2KDM4ECYP19A1 | |
| SCHEMBL7589137 | 0.84 | KDM4E (0.50) | LMNASMN1; SMN2KDM4ECYP19A1 | |
| SCHEMBL31040269 | 0.83 | SMN1; SMN2 (0.41) | LMNASMN1; SMN2KDM4EPRKDCKCNH2 | |
| SCHEMBL4899497 | 0.83 | HTT (0.45) | LMNASMN1; SMN2PRKDCKCNH2CYP1A2 | |
| SCHEMBL17865259 | 0.82 | CYP3A4 (0.42) | LMNASMN1; SMN2KDM4EPRKDCKCNH2 | |
| SCHEMBL4910223 | 0.80 | ALDH1A1 (0.50) | MAPK1IDO1CYP19A1CYP1A2 | |
| SCHEMBL5617833 | 0.76 | L3MBTL1 (0.58) | LMNASMN1; SMN2KDM4ECYP19A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004046141-A1 | NEW TRICYCLIC ANGIOTENSIN II AGONISTS | VICORE PHARMA AB (SE) | 2004-06-03 | — | — | WO | disclosed |