Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 12/20 | 0.64 |
| ▸ | EGFR | P00533 | 16/20 | 0.63 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.62 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.62 |
| ▸ | RET | P07949 | 1/20 | 0.55 |
| ▸ | KIF5B | P33176 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | LCK | P06239 | 1/20 | 0.51 |
| ▸ | KIT | P10721 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4726476 | 0.81 | CSF1R (0.64) | CSF1REGFRPDGFRBPDGFRARET | |
| SCHEMBL6181964 | 0.81 | EGFR (0.77) | CSF1REGFRPDGFRBPDGFRARET | |
| SCHEMBL3234222 | 0.80 | CSF1R (0.43) | CSF1REGFRPDGFRBPDGFRALMNA | |
| Hydrochloric Acid SCHEMBL6182000 | 0.80 | EGFR (0.78) | CSF1REGFRPDGFRBPDGFRARET | |
| SCHEMBL2257706 | 0.78 | CSF1R (1.00) | CSF1REGFRPDGFRBPDGFRARET | |
| SCHEMBL8177845 | 0.78 | EGFR (1.00) | CSF1REGFRPDGFRBPDGFRARET | |
| Hydrochloric Acid SCHEMBL6179746 | 0.77 | CSF1R (1.00) | CSF1REGFRPDGFRBPDGFRARET | |
| Hydrochloric Acid SCHEMBL6181342 | 0.77 | EGFR (1.00) | CSF1REGFRPDGFRBPDGFRARET | |
| SCHEMBL3529627 | 0.75 | CSF1R (0.53) | CSF1REGFRPDGFRBPDGFRARET | |
| SCHEMBL27490671 | 0.75 | CSF1R (0.58) | CSF1REGFRPDGFRBPDGFRARET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047489-A2 | COMPOSITIONS AND METHODS FOR USE IN CANCER THERAPY | ACADIA PHARMACEUTICALS INC. (US) | 2007-04-26 | — | — | WO | disclosed |