⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1723451 | 0.83 | — | — | |
| SCHEMBL835306 | 0.75 | — | — | |
| SCHEMBL17381336 | 0.75 | ALDH1A1 (0.42) | — | |
| SCHEMBL107778 | 0.75 | — | — | |
| Ethane SCHEMBL3782667 | 0.73 | — | — | |
| SCHEMBL7844269 | 0.73 | — | — | |
| SCHEMBL1010069 | 0.73 | — | — | |
| SCHEMBL22804225 | 0.73 | — | — | |
| Methane SCHEMBL782703 | 0.73 | — | — | |
| SCHEMBL28765622 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112341373-B | Preparation method of ftibamzone | 山东嘉成医药科技有限公司 | 2022-04-08 | — | — | CN | claimed |
| CN-112341373-A | Preparation method of ftibamzone | 山东嘉成医药科技有限公司 | 2021-02-09 | — | — | CN | claimed |
| CN-113039182-B | Inhibitors of YAP/TAZ-TEAD interactions and their use in cancer treatment | 伊文蒂瓦公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-112341373-B | Preparation method of ftibamzone | 山东嘉成医药科技有限公司 | 2022-04-08 | — | — | CN | disclosed |
| CN-112341373-B | Preparation method of ftibamzone | 山东嘉成医药科技有限公司 | 2022-04-08 | — | — | CN | disclosed |
| CN-113039182-A | Inhibitors of YAP/TAZ-TEAD interaction and their use in cancer treatment | 伊文蒂瓦公司 | 2021-06-25 | — | — | CN | disclosed |
| CN-112341373-A | Preparation method of ftibamzone | 山东嘉成医药科技有限公司 | 2021-02-09 | — | — | CN | disclosed |
| CN-112341373-A | Preparation method of ftibamzone | 山东嘉成医药科技有限公司 | 2021-02-09 | — | — | CN | disclosed |
| US-7309746-B2 | Polymers containing silane | WACKER POLYMER SYSTEMS GMBH & CO. KG (DE) | 2007-12-18 | — | — | US | disclosed |
| US-20050182223-A1 | Polymers containing silane | WACKER CHEMIE AG (DE) | 2005-08-18 | — | — | US | disclosed |
| CN-1630656-A | Dihydropyrazolopyridine compounds and pharmaceutical use thereof | MITSUBISHI PHARMA CORP (JP) | 2005-06-22 | — | — | CN | disclosed |
| EP-0823413-A2 | Benzoheterocyclic compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-02-11 | — | — | EP | disclosed |
| US-5591744-A | 1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXYLATE DERIVATIVES; MICROBIOCIDES | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1997-01-07 | — | — | US | disclosed |
| US-5563138-A | 4-OXOQUINOLINE-3-CARBOXYLIC ACID COMPOUNDS HAVING ANTIMICROBIAL ACTIVITY | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1996-10-08 | — | — | US | disclosed |
| EP-0287951-B1 | 7-Piperazinyl- or 7-Morpholino-4-oxo-quinoline-3-carboxylic acid derivatives, their preparation and their use as antimicrobial agents | OTSUKA PHARMA CO LTD (JP) | 1996-07-03 | — | — | EP | disclosed |
| US-5495020-A | CHEMICAL INTERMEDIATE FOR BACTERICIDES, MICROBIOCIDES, DISINFECTANTS; SIDE EFFECT REDUCTION, ABSORPTION | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1996-02-27 | — | — | US | disclosed |
| US-5420128-A | Pyrimidine derivatives, method of manufacturing the same, and androgen inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| US-5290934-A | Benzoheterocyclic compounds | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1994-03-01 | — | — | US | disclosed |
| EP-0565132-A2 | Benzoheterocyclic compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-10-13 | — | — | EP | disclosed |
| EP-0503099-A1 | PYRIMIDINE DERIVATIVE, PRODUCTION THEREOF, AND ANDROGEN INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-09-16 | — | — | EP | disclosed |