⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27275679 | 0.97 | — | — | |
| SCHEMBL832085 | 0.81 | — | — | |
| SCHEMBL834445 | 0.79 | — | — | |
| SCHEMBL28478024 | 0.77 | TSHR (0.46) | — | |
| SCHEMBL29011570 | 0.75 | — | — | |
| SCHEMBL706040 | 0.75 | — | — | |
| SCHEMBL17432055 | 0.75 | — | — | |
| SCHEMBL5618259 | 0.75 | — | — | |
| SCHEMBL20179681 | 0.72 | HIF1A (0.44) | — | |
| SCHEMBL1722348 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109771432-A | Application of the aminoglucose carbohydrates and their derivative as antiviral drugs | 中国人民解放军军事科学院军事医学研究院 | 2019-05-21 | — | — | CN | claimed |
| CN-101575329-B | Preparation method of tetrahydrothiophene-3-ketone and intermediate | CHONGQING FUAN PHARMACEUTICAL CO LTD | 2011-01-26 | — | — | CN | claimed |
| CN-101575329-A | Preparation method of tetrahydrothiophene-3-ketone and intermediate | CHONGQING FUAN PHARMACEUTICAL (CN) | 2009-11-11 | — | — | CN | claimed |
| CN-114681472-B | Application of glucosamine and derivatives thereof as antiviral drugs | 中国人民解放军军事科学院军事医学研究院 | 2023-06-30 | — | — | CN | disclosed |
| CN-114732822-B | Application of glucosamine and derivatives thereof as antiviral drugs | 中国人民解放军军事科学院军事医学研究院 | 2023-06-30 | — | — | CN | disclosed |
| CN-114732823-B | Application of glucosamine and derivatives thereof as antiviral drugs | 中国人民解放军军事科学院军事医学研究院 | 2023-05-23 | — | — | CN | disclosed |
| CN-114732822-A | Application of glucosamine and derivatives thereof as antiviral drugs | 中国人民解放军军事科学院军事医学研究院 | 2022-07-12 | — | — | CN | disclosed |
| CN-114732823-A | Application of glucosamine and derivatives thereof as antiviral drugs | 中国人民解放军军事科学院军事医学研究院 | 2022-07-12 | — | — | CN | disclosed |
| CN-114681472-A | Application of glucosamine and derivatives thereof as antiviral drugs | 中国人民解放军军事科学院军事医学研究院 | 2022-07-01 | — | — | CN | disclosed |
| CN-109771432-B | Application of glucosamine and derivatives thereof as antiviral drugs | 中国人民解放军军事科学院军事医学研究院 | 2022-04-19 | — | — | CN | disclosed |
| CN-112521350-A | Synthetic method of 3-methylamino tetrahydrofuran | 江苏广域化学有限公司 | 2021-03-19 | — | — | CN | disclosed |
| US-6096771-A | ISOXAZOLE DERIVATIVES EXHIBITING EXCELLENT TYPE B AND TYPE A MONOAMINE OXIDASE INHIBITORY ACTIVITIES, THEREFORE USEFUL FOR PREVENTING PARKINSON'S DISEASE, DEPRESSION AND ALZHEIMER'S DISEASE | SANKYO COMPANY, LIMITED (JP) | 2000-08-01 | — | — | US | disclosed |
| US-6005116-A | HAVE INHIBITION ACTIVITIES AGAINST TYPE A-MONOAMINE OXIDASE; TREATING OR PREVENTING DEPRESSION, PARKINSON'S DISEASE, ALZEHEIMER'S DEMENTIA, OR CEREBROVASCULAR DEMENTIA | SANKYO COMPANY, LIMITED (JP) | 1999-12-21 | — | — | US | disclosed |
| US-5965591-A | MONOAMINE OXIDASE INHIBITOR; FOR PROPHYLAXIS AND TREATING PARKINSON'S DISEASE, DEPRESSION AND ALZHEIMER'S DISEASE | SANKYO COMPANY, LIMITED (JP) | 1999-10-12 | — | — | US | disclosed |
| EP-0885891-A1 | ISOXAZOLE DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |
| EP-0542525-B1 | Antithrombotic agents | LILLY CO ELI (US) | 1998-07-08 | — | — | EP | disclosed |
| EP-0779281-A1 | ISOXAZOLES | SANKYO COMPANY LIMITED (JP) | 1997-06-18 | — | — | EP | disclosed |
| US-5250543-A | Hypotensive agents | LABORATOIRE L. LAFON (FR) | 1993-10-05 | — | — | US | disclosed |
| EP-0415704-A2 | Catalysts for polymerization of olefins | CHISSO CORPORATION (JP) | 1991-03-06 | — | — | EP | disclosed |
| EP-0105464-A2 | Textile finishes | SWS Silicones Corporation (US) | 1984-04-18 | — | — | EP | disclosed |