SCHEMBL561850

SCHEMBL561850

Cc1ccc(O)c(-n2nc3cc(Cl)c(Cl)cc3n2)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.71
RAB9A P51151 5/20 0.71
LMNA P02545 3/20 0.71
ALDH1A1 P00352 5/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
KDM4E B2RXH2 7/20 0.40
TRPA1 O75762 1/20 0.39
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39
MAPT P10636 4/20 0.39
HPGD P15428 3/20 0.39
TP53 P04637 2/20 0.39
ALOX15 P16050 2/20 0.39
HSD17B10 Q99714 2/20 0.39
GAA P10253 1/20 0.39
ALOX12 P18054 1/20 0.39
TDP1 Q9NUW8 2/20 0.38
POLB P06746 3/20 0.38
CYP1A2 P05177 1/20 0.37
CYP2C9 P11712 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29813507 1.00 NPC1 (0.71) NPC1RAB9ALMNAALDH1A1SMN1; SMN2
SCHEMBL12755301 0.86 NPC1 (0.75) NPC1RAB9ALMNAALDH1A1SMN1; SMN2
SCHEMBL3297579 0.86 NPC1 (0.81) NPC1RAB9ALMNAALDH1A1SMN1; SMN2
SCHEMBL30130370 0.86 NPC1 (0.69) NPC1RAB9ALMNAALDH1A1SMN1; SMN2
SCHEMBL698631 0.86 NPC1 (0.69) NPC1RAB9ALMNAALDH1A1SMN1; SMN2
SCHEMBL11424523 0.84 NPC1 (0.58) NPC1RAB9ALMNAALDH1A1SMN1; SMN2
Drometrizole SCHEMBL15616 0.83 NPC1 (1.00) NPC1RAB9ALMNAALDH1A1SMN1; SMN2
Drometrizole SCHEMBL2548258 0.83 NPC1 (1.00) NPC1RAB9ALMNAALDH1A1SMN1; SMN2
Drometrizole SCHEMBL27755727 0.83 NPC1 (1.00) NPC1RAB9ALMNAALDH1A1SMN1; SMN2
Drometrizole SCHEMBL29350665 0.83 NPC1 (1.00) NPC1RAB9ALMNAALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4144617-A None JP disclosed
JP-4131018-A None JP disclosed
EP-4083099-B1 VINYL CHLORIDE RESIN COMPOSITION AND MOLDED ARTICLE KURARAY CO (JP) 2025-07-23 EP disclosed
CN-115244113-B Multilayer film 日本玛泰株式会社 2024-03-29 CN disclosed
CN-114761458-B Multilayer film 日本玛泰株式会社 2024-02-27 CN disclosed
US-20230106407-A1 MULTILAYER FILM NIHON MATAI CO., LTD. (JP) 2023-04-06 US disclosed
EP-4129677-A1 MULTILAYER FILM Nihon Matai Co., Ltd. (JP) 2023-02-08 EP disclosed
US-20230002542-A1 THERMOPLASTIC POLYURETHANE FILM AND MULTILAYER FILM NIHON MATAI CO., LTD. (JP) 2023-01-05 US disclosed
US-20220363883-A1 VINYL CHLORIDE RESIN COMPOSITIONS AND SHAPED ARTICLES KURARAY CO., LTD. (JP) 2022-11-17 US disclosed
EP-4083099-A1 VINYL CHLORIDE RESIN COMPOSITION AND MOLDED ARTICLE Kuraray Co., Ltd. (JP) 2022-11-02 EP disclosed
US-4440843-A Electrophotographic copying process for forming positive or negative images OLYMPUS OPTICAL COMPANY LTD. (JP) 1984-04-03 US disclosed
US-4440844-A Electrophotographic copying process involving simultaneous charging and imaging OLYMPUS OPTICAL COMPANY LTD. (JP) 1984-04-03 US disclosed
US-4433038-A Electrophotographic copying process involving simultaneous charging and imaging OLYMPUS OPTICAL COMPANY LTD. (JP) 1984-02-21 US disclosed
US-4392737-A Electrophotographic copying apparatus OLYMPUS OPTICAL CO. LTD. (JP) 1983-07-12 US disclosed
EP-0065574-A1 PHOTOSYNTHETIC BACTERIA CULTURE NIPPON CARBIDE KOGYO KABUSHIKI KAISHA (JP) 1982-12-01 EP disclosed
US-4299886-A WITH POLYSILOXANES DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1981-11-10 US disclosed
US-4251435-A FOR POLYOLEFINS THE B. F. GOODRICH COMPANY (US) 1981-02-17 US disclosed
US-4235043-A Method for cultivating algae and a covering material used therefor Nippon Carbide Kogyo Kabashiki Kaisha (JP) 1980-11-25 US disclosed
US-3935164-A NICKEL 3,5-DI-TERT-ALKYL 4-HYDROXYBENZOATE, AND A BENZOPHENONE OR BENZOTRIAZOLE CIBA-GEIGY CORPORATION (US) 1976-01-27 US disclosed
US-3935163-A NICKEL BIS(3,5-DI-TERT-ALKYL-4-HYDROXY BENZOATE AND A BENZOPHENONE OR BENZOTRIAZOLE CIBA-GEIGY CORPORATION (US) 1976-01-27 US disclosed