Drometrizole

Drometrizole

SCHEMBL2548258

Cc1ccc(O)c(-n2nc3ccccc3n2)c1.Cc1ccc(O)c(-n2nc3ccccc3n2)c1.Cc1ccc(O)c(-n2nc3ccccc3n2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 8/20 1.00
RAB9A P51151 8/20 1.00
LMNA P02545 1/20 1.00
ALDH1A1 P00352 5/20 0.57
SMN1; SMN2 Q16637 5/20 0.57
KDM4E B2RXH2 4/20 0.56
POLB P06746 2/20 0.52
MAPT P10636 5/20 0.48
HPGD P15428 3/20 0.48
TDP1 Q9NUW8 2/20 0.48
NPSR1 Q6W5P4 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
IGF2BP2 Q9Y6M1 1/20 0.43
THRB P10828 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
TRPA1 O75762 1/20 0.42
MEN1 O00255 1/20 0.42
GAA P10253 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Drometrizole SCHEMBL15616 1.00 NPC1 (1.00) NPC1RAB9ALMNAALDH1A1SMN1; SMN2
Drometrizole SCHEMBL29350665 1.00 NPC1 (1.00) NPC1RAB9ALMNAALDH1A1SMN1; SMN2
Drometrizole SCHEMBL27755727 1.00 NPC1 (1.00) NPC1RAB9ALMNAALDH1A1SMN1; SMN2
Drometrizole SCHEMBL7796640 0.95 NPC1 (0.90) NPC1RAB9ALMNAALDH1A1SMN1; SMN2
Drometrizole SCHEMBL3793068 0.94 NPC1 (0.88) NPC1RAB9ALMNAALDH1A1SMN1; SMN2
Drometrizole SCHEMBL890036 0.94 NPC1 (0.88) NPC1RAB9ALMNAALDH1A1SMN1; SMN2
Drometrizole SCHEMBL6664698 0.94 NPC1 (0.88) NPC1RAB9ALMNAALDH1A1SMN1; SMN2
Drometrizole SCHEMBL6667186 0.89 NPC1 (0.80) NPC1RAB9ALMNAALDH1A1SMN1; SMN2
SCHEMBL3297579 0.89 NPC1 (0.81) NPC1RAB9ALMNAALDH1A1SMN1; SMN2
Drometrizole SCHEMBL15379 0.88 NPC1 (0.78) NPC1RAB9ALMNAALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9376533-B2 Structure directed vapour phase polymerisation of conductive polymers UNIVERSITY OF SOUTH AUSTRALIA (AU) 2016-06-28 US disclosed
US-20140288252-A1 STRUCTURE DIRECTED VAPOUR PHASE POLYMERISATION OF CONDUCTIVE POLYMERS UNIVERSITY OF SOUTH AUSTRALIA (AU) 2014-09-25 US disclosed
EP-2773678-A1 STRUCTURE DIRECTED VAPOUR PHASE POLYMERISATION OF CONDUCTIVE POLYMERS University Of South Australia (AU) 2014-09-10 EP disclosed
US-8537451-B2 Processes for producing electrochromic substrates and electrochromic articles made therefrom SMR PATENTS S.A.R.L. (LU) 2013-09-17 US disclosed
WO-2013052993-A1 STRUCTURE DIRECTED VAPOUR PHASE POLYMERISATION OF CONDUCTIVE POLYMERS UNIVERSITY OF SOUTH AUSTRALIA (AU) 2013-04-18 WO disclosed
US-20110261430-A1 PROCESSES FOR PRODUCING ELECTROCHROMIC SUBSTRATES AND ELECTROCHROMIC ARTICLES MADE THEREFROM SMR PATENTS S.A.R.L. (LU) 2011-10-27 US disclosed
EP-2123731-A1 Processes for producing electrochromic substrates and electrochromic articles made therefrom SMR PATENTS S.à.r.l. (LU) 2009-11-25 EP disclosed
WO-2009117761-A1 PROCESSES FOR PRODUCING ELECTROCHROMIC SUBSTRATES AND ELECTROCHROMIC ARTICLES MADE THEREFROM VISIOCORP AUSTRALIA PTY LTD (AU) 2009-10-01 WO disclosed
US-20050096405-A1 UV cured UV blocking compositions and methods for making and using the same DECO PATENTS, INC. 2005-05-05 US disclosed
EP-1463780-A4 UV CURED UV BLOCKING COMPOSITIONS AND METHODS FOR MAKING AND USING THE SAME DECO PATENTS INC (US) 2004-12-08 EP disclosed
EP-1463780-A2 UV CURED UV BLOCKING COMPOSITIONS AND METHODS FOR MAKING AND USING THE SAME DECO PATENTS, INC. (US) 2004-10-06 EP disclosed
US-20030109599-A1 UV cured UV blocking compositions and methods for making and using the same DECO PATENTS, INC. 2003-06-12 US disclosed
WO-2003006562-A9 UV CURED UV BLOCKING COMPOSITIONS AND METHODS FOR MAKING AND USING THE SAME DECO PATENTS INC (US) 2003-05-08 WO disclosed
WO-2003006562-A1 UV CURED UV BLOCKING COMPOSITIONS AND METHODS FOR MAKING AND USING THE SAME DECO PATENTS, INC. (US) 2003-01-23 WO disclosed