SCHEMBL698631

SCHEMBL698631

Cc1ccc(O)c(-n2nc3ccc(Cl)cc3n2)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 6/20 0.69
RAB9A P51151 5/20 0.69
LMNA P02545 1/20 0.69
KDM4E B2RXH2 5/20 0.42
ALDH1A1 P00352 3/20 0.42
HPGD P15428 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
MAPT P10636 5/20 0.39
TP53 P04637 2/20 0.39
ATM Q13315 2/20 0.39
GAA P10253 1/20 0.39
CASP1 P29466 1/20 0.39
CASP7 P55210 1/20 0.39
HSD17B10 Q99714 1/20 0.39
POLB P06746 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30130370 1.00 NPC1 (0.69) NPC1RAB9ALMNAKDM4EALDH1A1
SCHEMBL11418479 0.89 NPC1 (0.51) NPC1RAB9ALMNAKDM4EALDH1A1
SCHEMBL3297579 0.89 NPC1 (0.81) NPC1RAB9ALMNAKDM4EALDH1A1
SCHEMBL9638363 0.88 NPC1 (0.53) NPC1RAB9ALMNAKDM4EALDH1A1
SCHEMBL561850 0.86 NPC1 (0.71) NPC1RAB9ALMNAKDM4EALDH1A1
SCHEMBL29813507 0.86 NPC1 (0.71) NPC1RAB9ALMNAKDM4EALDH1A1
Bumetrizole SCHEMBL5353195 0.84 NPC1 (0.60) NPC1RAB9ALMNAKDM4EALDH1A1
SCHEMBL11424523 0.83 NPC1 (0.58) NPC1RAB9ALMNAKDM4EALDH1A1
SCHEMBL12755301 0.82 NPC1 (0.75) NPC1RAB9ALMNAKDM4EALDH1A1
Drometrizole SCHEMBL2548258 0.82 NPC1 (1.00) NPC1RAB9ALMNAKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106751559-A A kind of ultraviolet aging resistance PBAT thin-film materials and preparation method thereof 华南理工大学 2017-05-31 CN claimed
US-9447123-B2 Process for preparing 2-hydroxyphenyl alkenyl benzotriazole compounds; use of the said compounds obtained via the process in the synthesis of siloxane compounds containing a 2-hydroxyphenylbenzotriazole function L'OREAL (FR) 2016-09-20 US claimed
EP-2632904-B1 PROCESS FOR PREPARING 2-HYDROXYPHENYL ALKENYL BENZOTRIAZOLE COMPOUNDS AND PROCESS FOR PREPARING SILOXANE COMPOUNDS CONTAINING 2-HYDROXYPHENYL BENZOTRIZOLE FUNCTION ORÉAL L (FR) 2016-03-23 EP claimed
US-20130231488-A1 PROCESS FOR PREPARING 2-HYDROXYPHENYL ALKENYL BENZOTRIAZOLE COMPOUNDS; USE OF THE SAID COMPOUNDS OBTAINED VIA THE PROCESS IN THE SYNTHESIS OF SILOXANE COMPOUNDS CONTAINING A 2-HYDROXYPHENYLBENZOTRIAZOLE FUNCTION L'OREAL (FR) 2013-09-05 US claimed
EP-2632904-A1 PROCESS FOR PREPARING 2-HYDROXYPHENYL ALKENYL BENZOTRIAZOLE COMPOUNDS AND PROCESS FOR PREPARING SILOXANE COMPOUNDS CONTAINING 2-HYDROXYPHENYL BENZOTRIZOLE FUNCTION L'Oréal (FR) 2013-09-04 EP claimed
WO-2012055063-A1 PROCESS FOR PREPARING 2-HYDROXYPHENYL ALKENYL BENZOTRIAZOLE COMPOUNDS AND PROCESS FOR PREPARING SILOXANE COMPOUNDS CONTAINING 2-HYDROXYPHENYL BENZOTRIZOLE FUNCTION L'OREAL (FR) 2012-05-03 WO claimed
WO-2024135470-A1 ULTRAVIOLET LIGHT ABSORBING AGENT ミヨシ油脂株式会社 2024-06-27 WO disclosed
CN-117500882-A Polycarbonate resin composition and molded article 出光兴产株式会社 2024-02-02 CN disclosed
US-11739187-B2 Resin composition, production method thereof, molded product, multilayer structure, film, production method thereof, vapor deposition film, packaging material, vacuum packaging bag, vacuum insulator, thermoformed container, blow molded container, fuel container, and bottle-shaped container KURARAY CO., LTD. (JP) 2023-08-29 US disclosed
US-20230034325-A1 CONTAINER FOR, AND A PACK INCLUDING, CYANOACRYLATE COMPOSITION(S) HENKEL AG & CO KGAA (DE) 2023-02-02 US disclosed
CN-115494698-A Method for manufacturing semiconductor device and photoresist 台湾积体电路制造股份有限公司 2022-12-20 CN disclosed
US-20220089838-A1 RESIN MOLDING MATERIAL, METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING RESIN MEMBER OR THE LIKE MIYOSHI OIL & FAT CO., LTD. (JP) 2022-03-24 US disclosed
US-20200339771-A1 RESIN COMPOSITION, PRODUCTION METHOD THEREOF, MOLDED PRODUCT, MULTILAYER STRUCTURE, FILM, PRODUCTION METHOD THEREOF, VAPOR DEPOSITION FILM, PACKAGING MATERIAL, VACUUM PACKAGING BAG, VACUUM INSULATOR, THERMOFORMED CONTAINER, BLOW MOLDED CONTAINER, FUEL CONTAINER, AND BOTTLE-SHAPED CONTAINER KURARAY CO., LTD. (JP) 2020-10-29 US disclosed
EP-0031302-A2 Benzotriazole UV absorbers, process for their preparation and stabilized mixtures CIBA-GEIGY AG (CH) 1981-07-01 EP disclosed
US-4128559-A ANTIDEPRESSANT EASTMAN KODAK COMPANY (US) 1978-12-05 US disclosed
US-4077971-A ULTRAVIOLET ABSORBERS SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1978-03-07 US disclosed
US-4065427-A Polychromophoric heterocyclic ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1977-12-27 US disclosed
US-4041011-A FOR POLYMERS EASTMAN KODAK COMPANY (US) 1977-08-09 US disclosed
US-4000148-A POLYMERS EASTMAN KODAK COMPANY (US) 1976-12-28 US disclosed
US-3936418-A Benzotriazole ortho-ester ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1976-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130231488-A1 PROCESS FOR PREPARING 2-HYDROXYPHENYL ALKENYL BENZOTRIAZOLE COMPOUNDS; USE OF THE SAID COMPOUNDS OBTAINED VIA THE PROCESS IN THE SYNTHESIS OF SILOXANE COMPOUNDS CONTAINING A 2-HYDROXYPHENYLBENZOTRIAZOLE FUNCTION HPD, PAH, SULT2A1 NPC1 3298/4885RAB9A 4798/4885LMNA 762/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.