Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4D | Q6B0I6 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 2/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5619371 | 0.85 | KMT2A (0.46) | ADORA2BADORA2AKMT2AMAPK1CTSK | |
| SCHEMBL5619366 | 0.85 | KMT2A (0.46) | ADORA2BADORA2AKMT2AMAPK1CTSK | |
| SCHEMBL5618387 | 0.84 | CTSK (0.37) | ADORA2BADORA2AKMT2AMAPK1CTSK | |
| SCHEMBL5618694 | 0.84 | CTSK (0.37) | ADORA2BADORA2AKMT2AMAPK1CTSK | |
| SCHEMBL5619488 | 0.83 | ADORA2B (0.39) | ADORA2BADORA2AKDM4DCTSKSCN9A | |
| SCHEMBL5619489 | 0.83 | ADORA2B (0.39) | ADORA2BADORA2AKDM4DCTSKSCN9A | |
| SCHEMBL5619012 | 0.82 | KMT2A (0.39) | KMT2AMAPK1CTSK | |
| SCHEMBL5619497 | 0.82 | KMT2A (0.39) | KMT2AMAPK1CTSKSCN9A | |
| SCHEMBL5619494 | 0.82 | KMT2A (0.39) | KMT2AMAPK1CTSKSCN9A | |
| SCHEMBL5619552 | 0.79 | KDM4D (0.44) | KMT2AKDM4DSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7186843-B2 | potent antibacterial activity against various bacteria including drug-resistant strains | DAIICHI PHARMACEUTICAL CO. LTD. (JP) | 2007-03-06 | — | — | US | disclosed |