Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | HLCS | P50747 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9716566 | 0.98 | CYP1A2 (0.45) | CYP1A2HLCSCYP19A1TSHRHTT | |
| SCHEMBL10971582 | 0.94 | CYP1A2 (0.36) | CYP1A2CYP19A1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4333398 | 0.86 | NPC1 (0.36) | CYP1A2CYP19A1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2690407 | 0.84 | CYP1A2 (0.47) | CYP1A2HLCSCYP19A1ALDH1A1EPHX1 | |
| SCHEMBL30931491 | 0.82 | CYP1A2 (0.50) | CYP1A2HLCSCYP19A1ALDH1A1EPHX1 | |
| SCHEMBL4741801 | 0.82 | CYP1A2 (0.50) | CYP1A2HLCSCYP19A1ALDH1A1EPHX1 | |
| SCHEMBL30931490 | 0.82 | CYP1A2 (0.50) | CYP1A2HLCSCYP19A1ALDH1A1EPHX1 | |
| SCHEMBL2692573 | 0.82 | CYP1A2 (0.50) | CYP1A2HLCSCYP19A1ALDH1A1EPHX1 | |
| SCHEMBL30518306 | 0.82 | CYP1A2 (0.50) | CYP1A2HLCSCYP19A1ALDH1A1EPHX1 | |
| SCHEMBL8025402 | 0.82 | CYP1A2 (0.50) | CYP1A2HLCSCYP19A1ALDH1A1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8735322-B2 | Herbicides | SYNGENTA LIMITED (GB) | 2014-05-27 | — | — | US | disclosed |
| EP-2350034-B1 | NOVEL HERBICIDES | SYNGENTA LTD (GB) | 2013-08-28 | — | — | EP | disclosed |
| US-20120035053-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-02-09 | — | — | US | disclosed |
| EP-2350034-A1 | NOVEL HERBICIDES | Syngenta Limited (GB) | 2011-08-03 | — | — | EP | disclosed |
| WO-2010046194-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2010-04-29 | — | — | WO | disclosed |
| US-4803268-A | HERBICIDES, PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1989-02-07 | — | — | US | disclosed |
| EP-0061669-B1 | PROCESS FOR THE PREPARATION OF CYCLOHEXANE-1,3-DIONES, AND SOME BICYCLIC CYCLOHEXANE-1,3-DIONES | BASF Aktiengesellschaft (DE) | 1984-07-25 | — | — | EP | disclosed |
| EP-0061669-A1 | Process for the preparation of cyclohexane-1,3-diones, and some bicyclic cyclohexane-1,3-diones | BASF Aktiengesellschaft (DE) | 1982-10-06 | — | — | EP | disclosed |
| US-4028417-A | CARBOXYLIC OR PHOSPHORIC ACID AMIDES, SULFOXIDES OR SULFONES OR POLYOXYALKYLENE SOLVENTS | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035053-A1 | NOVEL HERBICIDES | DDT, HCAR3, HPD | CYP1A2 470/4885HLCS 1150/4885CYP19A1 537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.