⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16752565 | 1.00 | TRIM24 (0.33) | — | |
| Hydrochloric Acid SCHEMBL26963383 | 0.97 | TRIM24 (0.32) | — | |
| Ethylene SCHEMBL4674338 | 0.95 | TRIM24 (0.30) | — | |
| SCHEMBL17995298 | 0.91 | TRIM24 (0.39) | — | |
| SCHEMBL25608460 | 0.84 | — | — | |
| SCHEMBL8297545 | 0.75 | SRD5A1 (0.32) | — | |
| SCHEMBL21047670 | 0.74 | ALDH1A1 (0.38) | — | |
| SCHEMBL23733554 | 0.74 | MAPK1 (0.31) | — | |
| SCHEMBL8230997 | 0.72 | — | — | |
| SCHEMBL19706825 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070051-B1 | PROCESS FOR THE PRODUCTION OF R-(+)-6- CARBOXAMIDO- 3-N- METHYLAMINO- 1,2,3,4- TETRAHYDROCARBAZOLE | VERNALIS DEV LTD (GB) | 2015-06-03 | — | — | EP | claimed |
| JP-4756740-B2 | — | — | 2011-08-24 | — | — | JP | claimed |
| US-6359146-B1 | RESOLUTION OF ENANTIOMORPH MIXTURE | VERNALIS LIMITED (GB) | 2002-03-19 | — | — | US | claimed |
| CN-1305460-A | Process for preparation of R-(+)-6-carboxamido-3-N-methylamino-1,2,3,4-tetrahydrocarbazole | FINARIS CO LTD (GB) | 2001-07-25 | — | — | CN | claimed |
| EP-1070051-A1 | PROCESS FOR THE PRODUCTION OF R-(+)-6- CARBOXAMIDO- 3-N- METHYLAMINO- 1,2,3,4- TETRAHYDROCARBAZOLE | Vernalis Limited (GB) | 2001-01-24 | — | — | EP | claimed |
| WO-1999054302-A1 | PROCESS FOR THE PRODUCTION OF R-(+)-6- CARBOXAMIDO- 3-N- METHYLAMINO- 1,2,3,4- TETRAHYDROCARBAZOLE | VERNALIS LIMITED (GB) | 1999-10-28 | — | — | WO | claimed |
| EP-4674484-A2 | THIENOPYRROLE COMPOUNDS | Gilead Sciences, Inc. (US) | 2026-01-07 | — | — | EP | disclosed |
| EP-4291562-B1 | THIENOPYRROLE COMPOUNDS | GILEAD SCIENCES INC (US) | 2025-09-10 | — | — | EP | disclosed |
| US-20240217990-A1 | THIENOPYRROLE COMPOUNDS | GILEAD SCIENCES, INC. | 2024-07-04 | — | — | US | disclosed |
| US-20240217990-A1 | THIENOPYRROLE COMPOUNDS | GILEAD SCIENCES, INC. | 2024-07-04 | — | — | US | disclosed |
| CN-112313230-B | Novel compounds for the treatment, alleviation or prevention of conditions associated with Tau aggregate | AC免疫有限公司 | 2024-03-15 | — | — | CN | disclosed |
| EP-4291562-A1 | THIENOPYRROLE COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2023-12-20 | — | — | EP | disclosed |
| CN-116783202-A | Thienopyrrole compounds | 吉利德科学公司 | 2023-09-19 | — | — | CN | disclosed |
| EP-0588060-A2 | Method for preparing aromatic secondary amino compound | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1994-03-23 | — | — | EP | disclosed |
| US-4257952-A | PSYCHOTROPIC DRUGS, ANALGESICS, ANTIHISTAMINES | STERLING DRUG INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4226867-A | HYPOTENSIVE AGENTS | MERCK & CO., INC. (US) | 1980-10-07 | — | — | US | disclosed |
| EP-0010234-A1 | 3,3-Substituted spiro-1,2,4-benzothiadiazines and pharmaceutical compositions containing the same | MERCK & CO. INC. (US) | 1980-04-30 | — | — | EP | disclosed |
| US-4172834-A | ANALGESICS, ANTIHISTAMINES AND PSYCHOTROPIC AGENTS | STERLING DRUG INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4062864-A | ANALGESIC, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-3959309-A | ANALGESICS, PSYCHOTROPIC, ANTIHISTAMINE | STERLING DRUG INC. (US) | 1976-05-25 | — | — | US | disclosed |