Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.30 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16752565 | 0.95 | TRIM24 (0.33) | TRIM24TRIM33ESR2DRD2DRD4 | |
| SCHEMBL561992 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL26963383 | 0.92 | TRIM24 (0.32) | TRIM24TRIM33ESR2DRD2DRD4 | |
| SCHEMBL17995298 | 0.86 | TRIM24 (0.39) | TRIM24TRIM33ESR2DRD2DRD4 | |
| SCHEMBL25608460 | 0.80 | — | — | |
| SCHEMBL21997074 | 0.74 | — | — | |
| SCHEMBL8342263 | 0.72 | TGM2 (0.33) | — | |
| Ethylene SCHEMBL977547 | 0.72 | DRD3 (0.41) | DRD2DRD4DRD3 | |
| SCHEMBL8297545 | 0.71 | SRD5A1 (0.32) | — | |
| SCHEMBL21047670 | 0.70 | ALDH1A1 (0.38) | TRIM24TRIM33ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343503-B1 | HETEROARYL UREA NEUROPEPTIDE Y Y5 RECEPTOR ANTAGONISTS | SCHERING CORP (US) | 2008-11-12 | — | — | EP | disclosed |
| US-7309704-B2 | Heteroaryl urea neuropeptide Y Y5 receptor antagonists | SCHERING CORPORATION (US) | 2007-12-18 | — | — | US | disclosed |
| US-20060030588-A1 | Heteroaryl urea neuropeptide Y Y5 receptor antagonists | SCHERING CORPORATION | 2006-02-09 | — | — | US | disclosed |
| US-6982267-B2 | Heteroaryl urea neuropeptide Y Y5 receptor antagonists | SCHERING CORPORATION (US) | 2006-01-03 | — | — | US | disclosed |
| US-6946476-B2 | For therapy of metabolic and eating disorders such as obesity and hyperphagia, diabetes | SCHERING CORPORATION (US) | 2005-09-20 | — | — | US | disclosed |
| EP-1343503-A4 | HETEROARYL UREA NEUROPEPTIDE Y Y5 RECEPTOR ANTAGONISTS | SCHERING CORP (US) | 2004-03-17 | — | — | EP | disclosed |
| US-20040006086-A1 | Heteroaryl urea neuropeptide Y Y5 receptor antagonists | MERCK SHARP & DOHME CORP. | 2004-01-08 | — | — | US | disclosed |
| EP-1343503-A1 | HETEROARYL UREA NEUROPEPTIDE Y Y5 RECEPTOR ANTAGONISTS | Schering Corporation (US) | 2003-09-17 | — | — | EP | disclosed |
| US-20030055062-A1 | Heteroaryl urea neuropeptide Y Y5 receptor antagonists | SCHERING CORPORATION | 2003-03-20 | — | — | US | disclosed |
| WO-2002049648-A1 | HETEROARYL UREA NEUROPEPTIDE Y Y5 RECEPTOR ANTAGONISTS | SCHERING CORPORATION (US) | 2002-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055062-A1 | Heteroaryl urea neuropeptide Y Y5 receptor antagonists | NPY5R, NPY1R, NPY2R | TRIM24 4416/4885TRIM33 4157/4885ESR2 2584/4885 |
| US-20040006086-A1 | Heteroaryl urea neuropeptide Y Y5 receptor antagonists | NPY5R, NPY1R, NPY2R | TRIM24 4416/4885TRIM33 4157/4885ESR2 2584/4885 |
| US-20060030588-A1 | Heteroaryl urea neuropeptide Y Y5 receptor antagonists | NPY5R, NPY1R, NPY2R | TRIM24 4532/4885TRIM33 4086/4885ESR2 2524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.