SCHEMBL3064533

SCHEMBL3064533

O=C(C=Cc1cccc(Br)c1)c1ccc(OC2CCCCO2)cc1

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.50
GPR55 Q9Y2T6 1/20 0.50
BRAF P15056 1/20 0.48
KDR P35968 1/20 0.48
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
MAOB P27338 3/20 0.45
PTPN1 P18031 4/20 0.44
ALDH1A1 P00352 1/20 0.44
RELA Q04206 1/20 0.43
HSD17B3 P37058 1/20 0.43
MAOA P21397 1/20 0.42
P4HB P07237 1/20 0.42
NPC1 O15118 1/20 0.42
MAPT P10636 1/20 0.42
RAB9A P51151 1/20 0.42
CYP1B1 Q16678 2/20 0.41
CYP2D6 P10635 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30383983 1.00 ATM (0.50) ATMGPR55BRAFKDRCA1
SCHEMBL5619965 0.90 MAOB (0.53) CA1CA2MAOBPTPN1ALDH1A1
SCHEMBL5619972 0.90 MAOB (0.53) CA1CA2MAOBPTPN1ALDH1A1
SCHEMBL31233307 0.90 MAOB (0.53) CA1CA2MAOBPTPN1ALDH1A1
SCHEMBL25196614 0.87 MAOB (0.55) CA1CA2MAOBPTPN1ALDH1A1
SCHEMBL25223464 0.87 MAOB (0.55) CA1CA2MAOBPTPN1ALDH1A1
SCHEMBL5620399 0.87 CYP1B1 (0.53) MAOBALDH1A1RELAMAOANPC1
SCHEMBL5620395 0.87 CYP1B1 (0.53) MAOBALDH1A1RELAMAOANPC1
SCHEMBL5619991 0.85 MAPT (0.50) MAOBPTPN1ALDH1A1MAOAP4HB
SCHEMBL5619986 0.85 MAPT (0.50) MAOBPTPN1ALDH1A1MAOAP4HB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed
US-8618327-B2 Antibacterial agents and methods of use thereof WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2013-12-31 US disclosed
US-20120277252-A1 Antibacterial Agents and Methods of Use Thereof WISCONSIN ALUMNI RESEARCH FOUNDATION 2012-11-01 US disclosed
US-8227616-B2 Cyanopyridine antibacterial agents and methods of use thereof WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2012-07-24 US disclosed
US-20100261763-A1 ANTIBACTERIAL AGENTS AND METHODS OF USE THEREOF WISCONSIN ALUMNI RESEARCH FOUNDATION 2010-10-14 US disclosed
US-7737164-B2 Cyanopyridine antibacterial agents WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2010-06-15 US disclosed
WO-2008016738-A2 ANTIBACTERIAL AGENTS AND RELATED SCREENING METHODS USING SMALL MOLECULE MACROARRAYS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2008-02-07 WO disclosed
US-20080009528-A1 ANTIBACTERIAL AGENTS AND RELATED SCREENING METHODS USING SMALL MOLECULE MACROARRAYS WISCONSIN ALUMNI RESEARCH FOUNDATION 2008-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120277252-A1 Antibacterial Agents and Methods of Use Thereof FDPS, ABCG2, DUT ATM 3868/4885GPR55 3095/4885BRAF 1170/4885
US-20080009528-A1 ANTIBACTERIAL AGENTS AND RELATED SCREENING METHODS USING SMALL MOLECULE MACROARRAYS PCNA, ABCG2, API5 ATM 2798/4885GPR55 2222/4885BRAF 1133/4885
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B ATM 1722/4885GPR55 3772/4885BRAF 1908/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 ATM 1927/4885GPR55 4479/4885BRAF 2466/4885
US-20100261763-A1 ANTIBACTERIAL AGENTS AND METHODS OF USE THEREOF FDPS, CYP3A5, ABCG2 ATM 3994/4885GPR55 2658/4885BRAF 1174/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 ATM 1927/4885GPR55 4479/4885BRAF 2466/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.