Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | PTPRZ1 | P23471 | 3/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.52 |
| ▸ | KIF11 | P52732 | 2/20 | 0.50 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.44 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL777056 | 0.85 | ALDH1A1 (0.56) | ALDH1A1TDP1KDM4EPTPRZ1PTPN1 | |
| SCHEMBL28134224 | 0.82 | ALDH1A1 (0.54) | ALDH1A1TDP1KDM4EPTPRZ1PTPN1 | |
| Water SCHEMBL28356277 | 0.82 | ALDH1A1 (0.54) | ALDH1A1TDP1KDM4EPTPRZ1PTPN1 | |
| Fluoride SCHEMBL27372198 | 0.82 | ALDH1A1 (0.54) | ALDH1A1TDP1KDM4EPTPRZ1PTPN1 | |
| SCHEMBL29279435 | 0.82 | KIF11 (0.46) | ALDH1A1TDP1KDM4EPTPRZ1PTPN1 | |
| Hydrochloric Acid SCHEMBL27941541 | 0.80 | ALDH1A1 (0.52) | ALDH1A1TDP1KDM4EPTPRZ1PTPN1 | |
| SCHEMBL22795275 | 0.79 | TDP1 (0.52) | ALDH1A1TDP1KDM4EPTPRZ1PTPN1 | |
| SCHEMBL3896343 | 0.79 | TDP1 (0.86) | ALDH1A1TDP1KDM4EPTPRZ1PTPN1 | |
| SCHEMBL25118424 | 0.79 | KIF11 (0.43) | ALDH1A1TDP1KDM4EPTPRZ1PTPN1 | |
| SCHEMBL7491009 | 0.79 | KIF11 (0.43) | ALDH1A1TDP1KDM4EPTPRZ1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111825580-B | Method for synthesizing aromatic hydrocarbon trifluoromethylthio compound | 南京理工大学 | 2022-02-18 | — | — | CN | disclosed |
| CN-112375022-B | Preparation method of trifluoromethyl aryl sulfide | 江南大学 | 2022-01-11 | — | — | CN | disclosed |
| CN-110483347-B | Process for preparing substituted trifluoromethylsulfanyl benzenes from substituted anilines | 天津师范大学 | 2021-03-16 | — | — | CN | disclosed |
| CN-112375022-A | Preparation method of trifluoromethyl aryl sulfide | 江南大学 | 2021-02-19 | — | — | CN | disclosed |
| CN-110483350-B | Process for converting substituted phenyldiazonium salts into trifluoromethylsulfanylbenzenes | 天津师范大学 | 2021-01-05 | — | — | CN | disclosed |
| CN-111825581-A | Method for synthesizing trifluoromethylthio compound by using trifluoromethylsulfinyl chloride | 南京理工大学 | 2020-10-27 | — | — | CN | disclosed |
| CN-111825580-A | Method for synthesizing aromatic hydrocarbon trifluoromethylthio compound | 南京理工大学 | 2020-10-27 | — | — | CN | disclosed |
| CN-103804348-B | A kind of close electric trifluoromethylthio reagent, synthetic method and application thereof | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2015-10-14 | — | — | CN | disclosed |
| CN-102786537-B | Synthesis of economic and stable trifluoromethylthio copper (I) agent | UNIV FUZHOU | 2015-04-15 | — | — | CN | disclosed |
| CN-102786537-A | Synthesis of economic and stable trifluoromethylthio copper (I) agent | UNIV FUZHOU | 2012-11-21 | — | — | CN | disclosed |
| US-20040147764-A1 | Method for production of delta 1-pyrrolines | BAYER CROPSCIENCE AG (DE) | 2004-07-29 | — | — | US | disclosed |
| EP-1379500-A2 | METHOD FOR THE PRODUCTION OF $g(D)?1 PYRROLINES | Bayer CropScience AG (DE) | 2004-01-14 | — | — | EP | disclosed |
| CN-1422844-A | Intermediate for preparing substitated biphenyl oxazoline compounds | BAYER AG (DE) | 2003-06-11 | — | — | CN | disclosed |
| CN-1100768-C | Substituted biphenyl oxazolines | BAYER AG (DE) | 2003-02-05 | — | — | CN | disclosed |
| WO-2002081442-A2 | METHOD FOR THE PRODUCTION OF Δ1 PYRROLINES | BAYER CROPSCIENCE AG (DE) | 2002-10-17 | — | — | WO | disclosed |
| US-5998667-A | CHEMICAL INTERMEDIATE FOR INSECTICIDES, MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-12-07 | — | — | US | disclosed |
| US-5807877-A | Substituted biphenyl oxazolines | BAYER AKTIENGESELLSCHAFT (DE) | 1998-09-15 | — | — | US | disclosed |
| CN-1166832-A | Substituted biphenyl oxazolines | BAYER AG (DE) | 1997-12-03 | — | — | CN | disclosed |
| EP-0784617-A1 | SUBSTITUTED DIPHENYL OXAZOLINES | BAYER AG (DE) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996011190-A1 | SUBSTITUTED DIPHENYL OXAZOLINES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147764-A1 | Method for production of delta 1-pyrrolines | AR, NR5A1, SRD5A1 | ALDH1A1 110/4885TDP1 942/4885KDM4E 4271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.