⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3263840 | 0.72 | — | — | |
| SCHEMBL15753126 | 0.67 | — | — | |
| SCHEMBL31648666 | 0.62 | — | — | |
| SCHEMBL2532418 | 0.59 | CYP19A1 (0.32) | — | |
| SCHEMBL74453 | 0.57 | — | — | |
| SCHEMBL2513229 | 0.57 | — | — | |
| SCHEMBL10711617 | 0.57 | — | — | |
| SCHEMBL541690 | 0.56 | — | — | |
| SCHEMBL4352680 | 0.55 | — | — | |
| SCHEMBL129681 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247621-B2 | Antiviral phosphonate compounds and methods therefor | VALEANT RESEARCH & DEVELOPMENT (US) | 2007-07-24 | — | — | US | disclosed |
| US-20040023921-A1 | Antiviral phosphonate compounds and methods therefor | VRX HOLDCO LLC | 2004-02-05 | — | — | US | disclosed |