Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 1.00 |
| ▸ | ACHE | P22303 | 6/20 | 1.00 |
| ▸ | EP300 | Q09472 | 6/20 | 1.00 |
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | RAD52 | P43351 | 5/20 | 1.00 |
| ▸ | KDM1A | O60341 | 4/20 | 1.00 |
| ▸ | LMNA | P02545 | 4/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 3/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 2/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.83 |
| ▸ | POLB | P06746 | 1/20 | 0.83 |
| ▸ | GAA | P10253 | 1/20 | 0.83 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.83 |
| ▸ | RAC1 | P63000 | 2/20 | 0.80 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.80 |
| ▸ | MAOB | P27338 | 1/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.76 |
| ▸ | BCHE | P06276 | 2/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Palmitine SCHEMBL29471136 | 1.00 | CYP3A4 (1.00) | CYP3A4ACHEEP300MAPTRAD52 | |
| Palmitine SCHEMBL29350054 | 1.00 | CYP3A4 (1.00) | CYP3A4ACHEEP300MAPTRAD52 | |
| Palmitine SCHEMBL29376263 | 0.99 | CYP3A4 (1.00) | CYP3A4ACHEEP300MAPTRAD52 | |
| Palmitine SCHEMBL29766942 | 0.99 | CYP3A4 (1.00) | CYP3A4ACHEEP300MAPTRAD52 | |
| Palmitine SCHEMBL754702 | 0.99 | CYP3A4 (1.00) | CYP3A4ACHEEP300MAPTRAD52 | |
| Palmitine SCHEMBL2445279 | 0.99 | CYP3A4 (0.98) | CYP3A4ACHEEP300MAPTRAD52 | |
| Palmitine SCHEMBL29424483 | 0.98 | ACHE (1.00) | CYP3A4ACHEEP300MAPTRAD52 | |
| Palmitine SCHEMBL3321462 | 0.98 | ACHE (1.00) | CYP3A4ACHEEP300MAPTRAD52 | |
| SCHEMBL27137965 | 0.93 | CYP3A4 (0.87) | CYP3A4ACHEEP300MAPTRAD52 | |
| SCHEMBL27147420 | 0.92 | CYP3A4 (0.85) | CYP3A4ACHEEP300MAPTRAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3840 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122094689-A | Combination therapy of diacylglycerol kinase (DGK) alpha inhibitors with other therapies | — | 2026-05-26 | — | — | CN | claimed |
| CN-118305065-B | Aluminum alloy with surface loaded with bio-based antibacterial components and preparation method thereof | SHANDONG CHUANGXIN PRECISION TECHNOLOGY Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| CN-122031559-A | Purification and application method of self-assembled supermolecule based on decoction of radix puerariae, radix scutellariae and rhizoma coptidis | 上海交通大学 | 2026-05-15 | — | — | CN | claimed |
| EP-4687856-A2 | GLP-1R AGONIST AND DPP-4 INHIBITOR COMPOSITIONS AND METHODS OF USING | JDS Therapeutics, LLC (US) | 2026-02-11 | — | — | EP | claimed |
| US-12503455-B2 | Nucleic acid-binding photoprobes and uses thereof | ARRAKIS THERAPEUTICS, INC. (US) | 2025-12-23 | — | — | US | claimed |
| EP-4649136-A1 | GENETIC MODIFICATION OF MICROBES FOR PRODUCTION OF NITROGEN AND CARBON-CONTAINING COMPOUNDS | Fertis India Pvt Ltd (IN) | 2025-11-19 | — | — | EP | claimed |
| US-20250261667-A1 | BERBERINE ALKALOID FORMULATIONS IN THE PREVENTION AND/OR TREATMENT OF INFECTIOUS DISEASE | IRP Health Pty Ltd (AU) | 2025-08-21 | — | — | US | claimed |
| CN-120154607-A | Application of palmatine in preparation of pancreatic duct adenocarcinoma activity inhibitor | 杭州市第一人民医院(西湖大学附属杭州市第一人民医院) | 2025-06-17 | — | — | CN | claimed |
| CN-120084900-A | Quality detection method of uncaria antihypertensive preparation | 山东宏济堂制药集团股份有限公司 | 2025-06-03 | — | — | CN | claimed |
| CN-120064481-A | Method for optimizing classical name square Xiaoqiao decoction extraction process based on orthogonal combination reference association degree and AHP-entropy weight method | 陕西省中医医院 | 2025-05-30 | — | — | CN | claimed |
| CN-1259359-A | Xiongsanxian medicinal wine contg. bear bile and pseudo ginseng and its prepn. technology | YANG YUECHAO (CN) | 2000-07-12 | — | — | CN | claimed |
| US-6008356-A | BRBERINE SALT DERIVATIVE IS REACTED WITH SODIUM TETRABORATE AND POTASSIUM CARBONATE IN ALCOHOL SOLVEANT TO FORM INTERMEDIATE, REACTING INTERMEDIATE WITH ALKYL SUBSTITUENT IN ACETONITRILE SOLVENT, OXIDIZING THE FORMED INTERMEDIATE | HANWHA CORPORATION (KR) | 1999-12-28 | — | — | US | claimed |
| WO-1999055704-A1 | PHARMACEUTICALLY AVAILABLE PROTOBERBERINE SALTS DERIVATIVES, AND PROTOBERBERINE DERIVATIVES AND SALTS THEREOF | HANWHA CHEMICAL CORPORATION (KR) | 1999-11-04 | — | — | WO | claimed |
| US-5928645-A | EXTRACT CONTAINING BERBERINE AND A FLAVONOID | YOUNG BOK HAN & KOREAN ASSOC. OF CREATION RESEARCH (KR) | 1999-07-27 | — | — | US | claimed |
| CN-1220883-A | Medicine for treatment of adhesion and processing method | ZHIMIN DU (CN) | 1999-06-30 | — | — | CN | claimed |
| WO-1998000018-A1 | BERBERINE ALKALOIDS AS A TREATMENT FOR CHRONIC, PROTOZOALLY-INDUCED DIARRHEA | PRM PHARMACEUTICALS, INC. (US) | 1998-01-08 | — | — | WO | claimed |
| CN-1108549-A | External preparation of compound sweet wormwood oil | KUNMING PHARMACEUTICAL FACTORY (CN) | 1995-09-20 | — | — | CN | claimed |
| EP-0108147-B1 | USE OF A PROTOBERBERINE ALKALOID AND COMPOSITION CONTAINING SAME | MAROKO, Peter R. (US) | 1988-08-17 | — | — | EP | claimed |
| CN-86108482-A | Improving one's methods of preparation tetrahydropalmatine | — | 1987-09-09 | — | — | CN | claimed |
| US-4200629-A | BERBERINE ALKALOIDS, PHOSPHATES | NAKAMURA JUNICHI | 1980-04-29 | — | — | US | claimed |