Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Palmitine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 6/20 | 0.98 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 6/20 | 1.00 |
| ▸ | EP300 | Q09472 | 6/20 | 1.00 |
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | RAD52 | P43351 | 5/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 2/20 | 1.00 |
| ▸ | KDM1A | O60341 | 4/20 | 0.98 |
| ▸ | LMNA | P02545 | 4/20 | 0.98 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.98 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.98 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.81 |
| ▸ | RAC1 | P63000 | 2/20 | 0.81 |
| ▸ | POLB | P06746 | 1/20 | 0.81 |
| ▸ | GAA | P10253 | 1/20 | 0.81 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.81 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.79 |
| ▸ | MAOB | P27338 | 1/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Palmitine SCHEMBL29766942 | 1.00 | CYP3A4 (1.00) | CYP3A4EP300MAPTRAD52KDM4E | |
| Palmitine SCHEMBL754702 | 1.00 | CYP3A4 (1.00) | CYP3A4EP300MAPTRAD52KDM4E | |
| Palmitine SCHEMBL3321462 | 0.99 | ACHE (1.00) | CYP3A4EP300MAPTRAD52KDM4E | |
| Palmitine SCHEMBL29424483 | 0.99 | ACHE (1.00) | CYP3A4EP300MAPTRAD52KDM4E | |
| Palmitine SCHEMBL562120 | 0.99 | CYP3A4 (1.00) | CYP3A4EP300MAPTRAD52KDM4E | |
| Palmitine SCHEMBL29350054 | 0.99 | CYP3A4 (1.00) | CYP3A4EP300MAPTRAD52KDM4E | |
| Palmitine SCHEMBL29471136 | 0.99 | CYP3A4 (1.00) | CYP3A4EP300MAPTRAD52KDM4E | |
| Palmitine SCHEMBL2445279 | 0.98 | CYP3A4 (0.98) | CYP3A4EP300MAPTRAD52KDM4E | |
| SCHEMBL27137965 | 0.92 | CYP3A4 (0.87) | CYP3A4EP300MAPTRAD52KDM4E | |
| SCHEMBL27147420 | 0.91 | CYP3A4 (0.85) | CYP3A4EP300MAPTRAD52KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 260 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122051257-A | Preparation method and application of oxygen reduction electrocatalyst based on natural polyphenol | 天津科技大学 | 2026-05-15 | — | — | CN | claimed |
| CN-121583384-A | Nucleic acid-small molecule non-covalent complex and preparation method and application thereof | 上海中医药大学 | 2026-02-27 | — | — | CN | claimed |
| US-20250261667-A1 | BERBERINE ALKALOID FORMULATIONS IN THE PREVENTION AND/OR TREATMENT OF INFECTIOUS DISEASE | IRP Health Pty Ltd (AU) | 2025-08-21 | — | — | US | claimed |
| CN-119851100-B | Method and device for detecting surface damage precursor of additive manufacturing device | 中国人民解放军国防科技大学 | 2025-06-17 | — | — | CN | claimed |
| CN-119851100-A | Method and device for detecting surface damage precursor of additive manufacturing device | 中国人民解放军国防科技大学 | 2025-04-18 | — | — | CN | claimed |
| CN-119699475-A | Use of berberine alkaloid in preventing and/or treating intestinal diseases | IRP健康股份有限公司 | 2025-03-28 | — | — | CN | claimed |
| CN-119523997-A | Compound preparation of active ingredients of traditional Chinese medicine for inhibiting conversion of colorectal cancer and application thereof | 上海中医药大学附属龙华医院 | 2025-02-28 | — | — | CN | claimed |
| CN-118615346-B | Pharmaceutical composition for treating fungal infection and preparation method and application thereof | 江西普丽尔药业有限公司 | 2025-02-28 | — | — | CN | claimed |
| CN-119405656-A | Application of fibrauretine in preparing anti-hypoxia medicine | 中国人民解放军联勤保障部队第九〇四医院 | 2025-02-11 | — | — | CN | claimed |
| CN-119101047-A | Industrial production process of fibrauretine and its analogues | 四川定科制药有限公司 | 2024-12-10 | — | — | CN | claimed |
| CN-116322660-A | Micronutrient combinations to inhibit coronavirus cell infection | 马提亚斯·W·拉斯 | 2023-06-23 | — | — | CN | claimed |
| CN-115844908-A | Pharmaceutical composition containing fibrauretine, preparation method and application thereof | 威智医药有限公司 | 2023-03-28 | — | — | CN | claimed |
| CN-114163360-B | Synthesis and taste masking application of water-soluble biphenyl aromatic hydrocarbon | 天津师范大学 | 2023-03-24 | — | — | CN | claimed |
| CN-115006353-A | A nanometer sustained release preparation of fibrauretine extract with low adverse side effect, and its preparation method | 河南中盛动物药业有限公司 | 2022-09-06 | — | — | CN | claimed |
| CN-110376172-B | Method for identifying L-phenylalanine | 贵州大学 | 2022-05-17 | — | — | CN | claimed |
| CN-114371164-A | Pb based on gold aggregation induced by tetramer DNA dye2+And Tl+Visual detection method | 成都理工大学 | 2022-04-19 | — | — | CN | claimed |
| CN-114295594-A | Turn on type fluorescence sensor for screening triple helix DNA intercalators based on molecular beacon | 贵州理工学院 | 2022-04-08 | — | — | CN | claimed |
| CN-114288381-A | Application of photo-oxidation Zingiberaceae plant extract in antibacterial and antitumor drugs | 云南中医药大学 | 2022-04-08 | — | — | CN | claimed |
| CN-114163360-A | Synthesis and taste masking application of water-soluble biphenyl aromatic hydrocarbon | 天津师范大学 | 2022-03-11 | — | — | CN | claimed |
| CN-111388529-B | Pharmaceutical composition for treating onychomycosis and preparation method thereof | 云南西草资源开发有限公司 | 2022-03-01 | — | — | CN | claimed |