Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27977582 | 0.77 | TP53 (0.38) | CYP1A2TSHRMEN1CYP3A4CYP2D6 | |
| SCHEMBL27360524 | 0.75 | CYP1A2 (0.34) | CYP1A2TSHRMEN1CYP3A4CYP2D6 | |
| SCHEMBL1499930 | 0.74 | EPHX2 (0.46) | KMT2ANPC1EPHX2 | |
| SCHEMBL14899039 | 0.74 | EPHX2 (0.46) | KMT2ANPC1EPHX2 | |
| SCHEMBL11250069 | 0.74 | EPHX1 (0.33) | TSHRMEN1KMT2ATP53ACE | |
| SCHEMBL25763339 | 0.73 | GABRA1 (0.37) | TSHRTP53ACEGABRA1GABRA5 | |
| SCHEMBL12868795 | 0.71 | KMT2A (0.47) | CYP1A2TSHRMEN1CYP3A4CYP2D6 | |
| SCHEMBL12868800 | 0.71 | KMT2A (0.47) | CYP1A2TSHRMEN1CYP3A4CYP2D6 | |
| SCHEMBL15368063 | 0.71 | TP53 (0.50) | CYP1A2TSHRMEN1CYP2D6KMT2A | |
| SCHEMBL9181343 | 0.71 | TP53 (0.42) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120031556-A1 | Sacrificial Polymer Compositions Including Polycarbonates Having Repeat Units Derived from Stereospecific Polycyclic 2,3-Diol Monomers | PROMERUS LLC (US) | 2012-02-09 | — | — | US | disclosed |