SCHEMBL11250069

SCHEMBL11250069

CC1CC(C)C(C(C)C(=O)O)C(C)C1

nearest known ligand 0.33

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.33
GRM2 Q14416 1/20 0.33
GRM3 Q14832 1/20 0.33
ACE P12821 1/20 0.33
TP53 P04637 1/20 0.32
GABRA1 P14867 3/20 0.32
GABRA5 P31644 3/20 0.32
GABRB2 P47870 3/20 0.32
GABRR1 P24046 2/20 0.32
GABRA4 P48169 1/20 0.32
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
KMT2A Q03164 1/20 0.31
IDO1 P14902 1/20 0.31
TSHR P16473 1/20 0.31
TRPA1 O75762 2/20 0.30
TRPM8 Q7Z2W7 2/20 0.30
NPC1 O15118 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25784654 0.77 EPHX1 (0.46) EPHX1ALDH1A1TRPA1TRPM8
SCHEMBL28108983 0.77 EPHX1 (0.46) EPHX1ALDH1A1TRPA1TRPM8
SCHEMBL562410 0.74 CYP1A2 (0.41) ACETP53GABRA1GABRA5GABRB2
SCHEMBL1863233 0.73
SCHEMBL19865079 0.72 EPHX1 (0.38) EPHX1GRM2GRM3GABRR1MEN1
SCHEMBL19809897 0.72 EPHX1 (0.38) EPHX1GRM2GRM3GABRR1MEN1
SCHEMBL11247273 0.72 GRM2 (0.34) GRM2GRM3
SCHEMBL19155102 0.71 EPHX1 (0.40) EPHX1ACETP53GABRA1GABRA5
SCHEMBL10601493 0.70 TRPA1 (0.30) TRPA1TRPM8
SCHEMBL10280048 0.70 MEN1 (0.36) EPHX1ACETP53GABRA1GABRA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4321164-A 2,4,6-Trimethylcyclohexanemethanol and derivatives, process for preparing same and organoleptic uses thereof INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1982-03-23 US disclosed
US-4311602-A Use of 2,4,6-trimethylcyclohexanemethanol derivatives in augmenting or enhancing the aroma of dryer-added fabric softener articles INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1982-01-19 US disclosed
US-4301022-A COMPRISING THE ACETIC ACID ESTER AND THE CYCLOHEXENE COMPOUNDS INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1981-11-17 US disclosed
US-4289146-A Use of 2,4,6-trimethylcyclohexanemethanol and derivatives for augmenting or enhancing the aroma or taste of smoking tobacco and smoking tobacco articles INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1981-09-15 US disclosed
US-4282205-A 2,4,6-Trimethylcyclohexanemethanol and derivatives, process for preparing same and organoleptic uses thereof INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1981-08-04 US disclosed