Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.45 |
| ▸ | METAP1 | P53582 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8077011 | 1.00 | ACHE (0.45) | ACHEMETAP1KDM4EMEN1MAPT | |
| SCHEMBL7998826 | 0.85 | ACHE (0.59) | ACHEMETAP1KDM4EMEN1MAPT | |
| SCHEMBL1093558 | 0.85 | ACHE (0.59) | ACHEMETAP1KDM4EMEN1MAPT | |
| SCHEMBL32679178 | 0.85 | ACHE (0.59) | ACHEMETAP1KDM4EMEN1MAPT | |
| SCHEMBL32679177 | 0.85 | ACHE (0.59) | ACHEMETAP1KDM4EMEN1MAPT | |
| SCHEMBL388171 | 0.85 | ACHE (0.59) | ACHEMETAP1KDM4EMEN1MAPT | |
| SCHEMBL30737574 | 0.85 | ACHE (0.59) | ACHEMETAP1KDM4EMEN1MAPT | |
| SCHEMBL5902891 | 0.81 | ACHE (0.55) | ACHEMETAP1KDM4EMEN1MAPT | |
| SCHEMBL3867845 | 0.81 | ANPEP (0.42) | — | |
| SCHEMBL5271544 | 0.81 | ANPEP (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057479-A | MULTISTAGE REACTION OF HYDROXY INDANONE WITH AMINE TO FORM IMINE, HEATING AND HYDROGENATION | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |